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N1161

Sigma-Aldrich

还原型 β-烟酰胺腺嘌呤二核苷酸 二钠盐 水合物

~98%, pkg of 100 mg

同義詞:

β-DPNH, β-NADH, 辅酶I还原型二钠盐, 还原型二磷酸吡啶核苷酸, DPNH, NADH, 二磷酸吡啶核苷酸，还原形式

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About This Item

經驗公式（希爾表示法）:
C21H27N7Na2O14P2 · xH2O
CAS號碼:
606-68-8
分子量：:
709.40 (anhydrous basis)
MDL號碼:
MFCD03791273
分類程式碼代碼:
41106305
PubChem物質ID:
329818507
NACRES:
NA.51

化驗

~98%

品質等級

200

形狀

powder

包裝

pkg of 100 mg

儲存溫度

−20°C

SMILES 字串

O.[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@@H]2O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O

InChI

1S/C21H29N7O14P2.2Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;;1H2/q;2*+1;/p-2/t10-,11-,13-,14-,15-,16-,20-,21-;;;/m1.../s1

InChI 密鑰

FWBNCIFELNNJCX-UHOVGGJYSA-L

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應用

作为一种试剂，NADH可用于酶循环测定，以扩大对低浓度含量的生物相关酶或代谢物活性的检测。

生化／生理作用

NADH是一种辅酶，其在糖酵解、氧化和柠檬酸循环(Krebs循环、TCA循环)等分解代谢过程中起着再生电子供体的作用。它也参与细胞信号事件，例如在DNA损伤反应过程中作为多聚(ADP-核糖)聚合酶(PARPs)的底物。NAD+/NADH依赖的去乙酰化酶在能量代谢过程中的应激反应中发挥关键作用，在癌症生物学、糖尿病和神经退行性疾病中具有重要意义。
作为一种试剂，NADH可用于酶循环测定，以扩大对低浓度含量的生物相关酶或代谢物活性的检测。

包裝

依固体重量包装。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析證明 (COA)

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