MAK475

Creatinine Assay Kit

sufficient for 100 colorimetric or fluorometric tests

• 分類程式碼代碼: 12352204
• NACRES: NA.84

屬性

• 品質等級: 100
• 檢測方法: colorimetric; fluorometric
• 相關疾病: renal disease; neurological disorders; genitourinary disorders
• 運輸包裝: wet ice
• 儲存溫度: −20°C

描述

一般說明

Creatinine is synthesized in the body from creatine, which is produced from creatine phosphate during muscle contractions. In the blood, creatinine is removed by filtration through the glomeruli of the kidney and is secreted into urine. In healthy individuals, creatinine secretion is independent of diet and is fairly constant. The creatinine clearance test has become one of the most sensitive tests for measuring glomerular filtration rate. In kidney disease, creatinine levels in the blood are elevated, whereas the creatinine clearance rate and subsequent creatin levels in urine are diminished. Creatinine testing is most widely used to assess kidney function.

特點和優勢

• The linear detection range of creatinine is 4.8 to 500 µM (0.054 - 5.7 mg/dL) for the colorimetric assay and 0.25 to 100 µM (0.0028 - 1.14 mg/dL) for the fluorometric assay.
• Compatible with high-throughput handling systems.
• Convenient. The procedure involves adding a single working reagent and reading after 60 minutes.

適合性

The kit is suitable for creatinine determination in urine, serum, plasma, and other biological preparations.

原則

The Creatinine Assay Kit uses a reaction sequence to convert a dye into a colored and fluorescent form. The absorbance at 570 nm or fluorescence intensity at λEx = 530 nm/λEm = 585 nm is directly proportional to the creatinine concentration in the sample. The reaction specifically excludes both endogenous creatine and ammonia.

安全資訊

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H334
• 防範說明: P261 - P284 - P501
• 危險分類: Resp. Sens. 1
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3