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Key Documents

M5170

Sigma-Aldrich

IgM, Lambda 来源于鼠骨髓瘤

clone MOPC 104E, purified immunoglobulin, buffered aqueous solution

同義詞:

小鼠IgM-λ

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

mouse

共軛

unconjugated

抗體表格

purified immunoglobulin

無性繁殖

MOPC 104E, monoclonal

形狀

buffered aqueous solution

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

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一般說明

IgM antibodies are present as pentamers in the serum and are produced in response to antigens
IgM, λ from murine myeloma is produced by MOPC 104E tumor line introduced subcutaneously in BALB/c mice. It specifically recognizes mouse IgM, λ. Identity and purity of the immunoglobulin is established by immunoelectrophoresis.

特異性

抗原特异性:α(1→3)葡萄糖

應用

IgM, λ from murine myeloma was used as standard in ELISA and as isotype control in immunohistochemistry applications.

生化/生理作用

IgM antibodies are produced initially during B-cell development. IgM participates in opsonization and compliment fixation. Defect in IgM production is observed in X-linked agammaglobulinemia.

外觀

Solution in 0.05 M Tris, 0.5 M sodium chloride, pH 8.0, containing 0.02% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Establishment of fetal bovine intestinal epithelial cell cultures susceptible to bovine rotavirus infection
Kaushik RS et al
J. Virol. Methods, 148, 182-196 (2008)
Jason R Nesbitt et al.
Frontiers in microbiology, 8, 2706-2706 (2018-02-07)
Aspergillus fumigatus is a filamentous fungus that can cause a life-threatening invasive pulmonary aspergillosis (IPA) in immunocompromised individuals. We previously characterized an exo-sialidase from A. fumigatus that prefers the sialic acid substrate, 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (Kdn); hence it is a Kdnase.
D R Wilson et al.
Protein engineering, 10(5), 531-540 (1997-05-01)
The immunodominant region of the Plasmodium falciparum circumsporozoite protein is comprised mainly of a series of tetrapeptide repeats that can, depending on the starting cadence chosen, be described as (NANP)n, (ANPN)n, (NPNA)n or (PNAN)n in one-letter amino acid code. Data
Radhey S Kaushik et al.
Journal of virological methods, 148(1-2), 182-196 (2008-01-12)
Mucosal epithelial cells are infected by a wide variety of pathogens and determining their response to infection is critical for understanding disease pathogenesis. A protocol was developed for culturing primary epithelial cells from fetal bovine intestine and the cultured cells
Chithra C Sreenivasan et al.
Virology, 528, 152-163 (2019-01-08)
Influenza viruses are a group of respiratory pathogens that have evolved into four different types: A, B, C, and D. A common feature is that all four types are capable of replicating and transmitting among pigs. Here, we describe the

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