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Key Documents

L5647

Sigma-Aldrich

利多卡因 盐酸盐 一水合物

≥99% (HPLC), solid, Na⁺ channel blocker

同義詞:

2-二乙氨基-N-(2,6-二甲苯基)乙酰胺 盐酸盐 一水合物, 利多卡因 盐酸盐 一水合物, 赛洛卡因 盐酸盐 一水合物

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About This Item

經驗公式(希爾表示法):
C14H22N2O · HCl · H2O
CAS號碼:
分子量::
288.81
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

product name

利多卡因 盐酸盐 一水合物, solid

形狀

solid

品質等級

顏色

white

溶解度

H2O: soluble

SMILES 字串

Cl[H].[H]O[H].CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2

InChI 密鑰

YECIFGHRMFEPJK-UHFFFAOYSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

Lidocaine hydrochloride monohydrate is a commonly used as local anesthetic in topical applications and oral mucosal biopsies. It has a short anesthetic half-life.

應用

Lidocaine hydrochloride monohydrate has been used:
  • in the preparation of drug composite for the controlled delivery in vitro, evaluated by drug release profile in ultra-high performance liquid chromatography (UPLC) and as a reference standard for fourier transform infrared spectroscopy (FT-IR).
  • to record dose dependent response of sodium voltage (Nav1.7) channels in the injection-molded polymer device.
  • For inhibition of glial cells in brain tissue samples.

生化/生理作用

Na+ 通道阻滞剂;IB 类抗心律失常药,在肠胃外给药后迅速吸收

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

防範說明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


分析證明 (COA)

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Ion channel recordings on an injection-molded polymer chip
Tanzi S, et al.
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HIV-1 Tat-induced diarrhea evokes an enteric glia-dependent neuroinflammatory response in the central nervous system
Esposito G, et al.
Scientific Reports, 7(1), 7735-7735 (2017)
Functionalized silver doped hydroxyapatite scaffolds for controlled simultaneous silver ion and drug delivery
Dubnika A, et al.
Ceramics International, 43(4), 3698-3705 (2017)
Giovanni Sarnelli et al.
Journal of neuroinflammation, 15(1), 94-94 (2018-03-27)
Diarrhea is a severe complication in HIV-1-infected patients with Trans-activator of transcription (HIV-1 Tat) protein being recognized as a major underlying cause. Beside its direct enterotoxic effects, Tat protein has been recently shown to affect enteric glial cell (EGC) activity.
Päivi Ylä-Anttila et al.
Methods in enzymology, 452, 143-164 (2009-02-10)
Electron microscopy remains one of the most accurate methods for the detection of autophagy and quantification of autophagic accumulation. Compared to fluorescence microscopy, the resolution of transmission electron microscopy is superior. In this chapter we describe the fine structure of

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