L1026

利多卡因

analytical standard

• 同義詞: 2-二乙氨基-N-（2,6-二甲苯基）乙酰胺, 利多卡因, 赛洛卡因
• 經驗公式（希爾表示法）: C₁₄H₂₂N₂O
• CAS號碼: 137-58-6
• 分子量：: 234.34
• EC號碼: 205-302-8
• MDL號碼: MFCD00026733
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24896272
• NACRES: NA.77

屬性

• 等級: analytical standard
• 形狀: solid
• 包裝: vial of 200 mg
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 雜質: ≤0.5% Total Organic Impurities (Lidocaine related compound H ≤0.10%; ; ; 2,6-Dimethylaniline ≤0.01%; ; ; Any unspecified impurity ≤0.10%; ; ; Total impurities ≤0.5%)
• 應用: forensics and toxicology; pharmaceutical (small molecule)
• SMILES 字串: CCN(CC)CC(=O)Nc1c(C)cccc1C
• InChI: 1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
• InChI 密鑰: NNJVILVZKWQKPM-UHFFFAOYSA-N
• 基因資訊: human ... CYP1A2(1544) , SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335) ; rat ... Scnn1a(25122)

描述

一般說明

Lidocaine is an amide anesthetic, which is used to treat ventricular arrhythmias. It lowers cardiac automaticity and myocardial conduction. Lidocaine inhibits the generation and conduction of nerve impulses. It has an anticonvulsant effect.

應用

Lidocaine has been used to examine its effects in inhibiting lymph flow and protection against envenomation. It has also been used to assess its efficacy as an anti-tussive agent.

生化／生理作用

Na⁺通道阻滞剂；IB类抗心律失常药。

Na⁺通道阻滞剂；在肠胃外给药后可迅速被吸收的IB类抗心律失常药。

包裝

Supplied in amber screw-cap vials

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P264 - P270 - P301 + P312 - P501
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Faceshields, Gloves