推薦產品
mp
96-99 °C (lit.)
儲存溫度
2-8°C
SMILES 字串
OCc1c[nH]c2ccccc12
InChI
1S/C9H9NO/c11-6-7-5-10-9-4-2-1-3-8(7)9/h1-5,10-11H,6H2
InChI 密鑰
IVYPNXXAYMYVSP-UHFFFAOYSA-N
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一般說明
吲哚-3-甲醇是十字花科蔬菜中产生的一种新的次生植物代谢产物，例如卷心菜、花椰菜和抱子甘蓝等。
應用
吲哚-3-甲醇用于封装聚-乳酸-co-乙醇酸 (PLGA)，以研究其对乳腺腺癌上皮细胞(MCF7)、结肠腺癌上皮细胞(Caco2)、前列腺癌上皮细胞(PC3)的体外抗癌效果。它还被用作细胞色素P4501A (CYP1A)诱导物。
生化／生理作用
吲哚-3-甲醇(I3C)激活芳烃受体(AhR)，诱导G1细胞周期阻滞和凋亡。因此，它是一种潜在的抗癌剂。此外，它通过刺激细胞色素P450酶来诱导雌二醇代谢。因此，I3C被认为是一种有效的化疗药物，用于各种类型的癌症，包括乳腺癌、前列腺癌、结肠癌和白血病。
在起始阶段抑制致癌症发生。已经证明在几种动物中具有抑制癌症发生的作用，但如果在发病后阶段给药，它会增加肿瘤的发病率。 在十字花科蔬菜中发现。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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