推薦產品
product name
艾地苯醌, ≥98% (HPLC)
化驗
≥98% (HPLC)
形狀
powder
溶解度
methanol: 50 mg/mL, clear to slightly hazy
儲存溫度
room temp
SMILES 字串
O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O
InChI
1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3
InChI 密鑰
JGPMMRGNQUBGND-UHFFFAOYSA-N
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一般說明
艾地苯醌是一种短链苯醌类药物。
應用
艾地苯醌已用于:
- 处理用于药物治疗测定的突变肌纤蛋白 (mMYOC)细胞
- 验证 C2C12 二次细胞筛选测定
- 处理肥胖小鼠,测试艾地苯醌和 CoQ10 是否直接结合过氧化物酶体增殖物激活受体(PPAR)LBD、His 标记的 PPAR αδ 和γ LBD。
生化/生理作用
艾地苯醌用于治疗患有 Leber′遗传性视神经病变 (LHON)的青少年和成人的视力障碍。它可用作抗氧化剂。它有助于保护心肌免于氧化应激。
一种短链辅酶 Q 类似物,可通过介导电子从 N2 转移到氧来增强超氧化物的形成。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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Friedreich ataxia is a rare inherited autosomal recessive neurological disorder, characterised initially by unsteadiness in standing and walking, slowly progressing to wheelchair dependency usually in the late teens or early twenties. It is associated with slurred speech, scoliosis and pes
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The knowledge of the interactions between solid lipid nanoparticles (SLN) and cell membranes is important to develop effective carrier systems for drug delivery applications. Loading idebenone (IDE), an antioxidant drug useful in the treatment of neurodegenerative diseases, into SLN improves
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Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 32(4), 386-389 (2012-12-01)
Bioorganic & medicinal chemistry, 21(4), 969-978 (2013-01-15)
Two new aza analogues of the neuroprotective agent idebenone have been synthesized and characterized. Their antioxidant activity, and ability to augment ATP levels have been evaluated in several different cell lines having suboptimal mitochondrial function. Both compounds were found to
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
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