GE11-0034-93

HiTrap^® MabSelect SuRe^™

Cytiva 11-0034-93, pack of 5 × 1 mL

• 分類程式碼代碼: 23151816
• NACRES: NA.56

屬性

• ligand: alkali-stabilized protein A-derived (E. coli)
• 儲存期限: Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
• 包裝: pack of 5 × 1 mL
• 製造商／商標名: Cytiva 11-0034-93
• 儲存條件: (20% Ehtanol); (20% Ethanol)
• 參數: flow rate; <4 ml/min flow rate (1)The pressure over the packed bed varies depending on a range of parameters such as the characteristics of the chromatography medium and the column tubing used.); 42 psi
• 床尺寸: 7 mm × 25 mm
• 床體積: 1 mL
• 柱內徑: 7 mm
• 基質: highly cross-linked agarose
• 樣品平均尺寸: 85 μm (d₅₀v is the median particle size of the cumulative volume distribution)
• cleaning: 2-13.7(pH below 3 is sometimes required to elute strongly bound IgG species. However, protein ligands may hydrolyze at very low pH.)
• 工作範圍: 3-12(pH below 3 is sometimes required to elute strongly bound IgG species. However, protein ligands may hydrolyze at very low pH.)
• 容量: ≥30 mg binding capacity (humanlgG/ml at 2.4 min residence time)(Determined at 10% breakthrough by frontal analysis at a mobile phase velocity of 500 cm/h in a column with a bed height of 20 cm.)
• 適合性: suitable for bioprocess medium
• 儲存溫度: 2-8°C

描述

一般說明

HiTrap^® MabSelect^™ SuRe^™ columns are prepacked with MabSelect^™ SuRe, a BioProcess medium for purification of monoclonal antibodies from large sample volumes. The novel alkali-tolerant recombinant Protein A ligand allow cleaning-in-place (CIP).

HiTrap^® MabSelect^™ columns are prepacked with MabSelect^™ a bioprocess medium for capuring of Mabs from large sample volumes.

特點和優勢

• Withstands rigorous CIP and sanitization procedures with 0.1 to 0.5 M NaOH.
• Novel ligand design gives enhanced protease resistance resulting in lower ligand leakage.
• Oriented coupling of recombinant Protein A to the matrix via an engineered C-terminal cysteine enhances IgG binding capacity.
• Fewer regulatory concerns due to the total absence of mammalian culture in the ligand production and purification.
• Prepacked HiTrap^® columns for process development, screening of purification conditions, and small-scale purification of Mabs.

分析報告

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

法律資訊

Free MabSelect SuRe Ligand
"MabSelect SuRe Ligand Restricted License" and "Cys-rProtein A Ligand Restricted License" are protected by the following patents and equivalent patents and patent applications in other countries: US 6,399,750 and EP 1123389. A free, non-transferable limited license to use this product for internal analytical purposes only accompanies the purchase of the product from a Cytiva company and its licensed distributors. Any other use will require a separate license from a Cytiva company.

HiTrap is a registered trademark of Cytiva

MabSelect is a trademark of Cytiva

MabSelect SuRe is a trademark of Cytiva

SuRe is a trademark of Cytiva

安全資訊

• 象形圖: GHS02
• 訊號詞: Warning
• 危險聲明: H226
• 防範說明: P210 - P235 - P241 - P280 - P303 + P361 + P353 - P501
• 儲存類別代碼: 3 - Flammable liquids