G9548
光甘草定
≥98% (HPLC), powder, isoflavan
同義詞:
4-[(3R)-3,4-二氢-8,8-二甲基-2H,8H-苯并 [1,2-b:3,4-b′] 二吡喃-3-基]-1,3-苯二酚, 光甘草定, (R)-4-（3,4-二氢-8,8-二甲基-2 H,8 H-苯并 [1,2-b:3,4-b'] 二吡喃-3-基）-1,3-苯二酚
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About This Item
經驗公式（希爾表示法）:
C20H20O4
CAS號碼:
分子量：:
324.37
Beilstein:
7141956
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推薦產品
product name
光甘草定, ≥98% (HPLC), powder
化驗
≥98% (HPLC)
形狀
powder
顏色
white to light brown
溶解度
DMSO: 5 mg/mL, clear (warmed)
儲存溫度
room temp
SMILES 字串
CC1(C)Oc2ccc3C[C@@H](COc3c2C=C1)c4ccc(O)cc4O
InChI
1S/C20H20O4/c1-20(2)8-7-16-18(24-20)6-3-12-9-13(11-23-19(12)16)15-5-4-14(21)10-17(15)22/h3-8,10,13,21-22H,9,11H2,1-2H3/t13-/m0/s1
InChI 密鑰
LBQIJVLKGVZRIW-ZDUSSCGKSA-N
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應用
光甘草定已被用于：
- 分析其在健康志愿者血浆中的转甲状腺素蛋白（TTR）稳定作用
- 作为质子核磁共振（1H NMR）中的标准品用于通过多光谱和分子对接（multi-spectroscopic and molecular docking ）技术研究光甘草定和人血清球蛋白的相互作用
- 研究其对核苷酸结合寡聚化结构域样受体Pyrin域蛋白3（NLRP3）炎症小体活化的作用
生化／生理作用
光甘草定是glavonoid 的主要成分，也称为来源于甘草的黄酮油，是用于传统医学和草药的天然增补剂。
光甘草定是一种可生物利用的异黄烷，是从甘草（洋甘草 ）根部提取物分离而来。据报道光甘草定具有多种生物活性，包括强抗氧化活性、 抗 LDL 氧化活性、抗-幽门螺旋杆菌性质、类雌激素活性和自由基清除活性。 它也可以抑制血清素再摄取、黑素生成、发炎和细胞色素P450、3A4、2B6和2C9。
訊號詞
Warning
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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