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一般說明
Vitamin D binding protein (DBP) is a polymorphic protein that specifically binds to vitamin D and its metabolites. This protein belongs to the albuminoid family and is highly conserved among vertebrates. The gene encoding DBP is mapped to human chromosome 4q11-q13. It is predominantly produced in the liver and is also expressed in the kidney, endocrine pancreatic cells, fat cells, and testis.
應用
Globulins were used in Biotin/avidin formulations.
生化／生理作用
Vitamin D binding protein (DBP) specifically binds and transports vitamin D and its metabolites with high affinity. It promotes fibrillar actin clearance by binding to actin monomers. DBP also binds to unsaturated fatty acids, megalin-cubilin receptor complex, the membrane of leukocytes, and the activation of the complement C5 system. The levels of DBP indicate the free concentration of all vitamin D metabolites. Decreased levels of serum DBP are observed in liver diseases, nephrotic syndrome, malnutrition, severe acute trauma, or disease.
其他說明
Primarily γ-globulins
外觀
Lyophilized powder containing NaCl
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
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