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Merck
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Key Documents

G4796

Sigma-Aldrich

京尼平

≥98% (HPLC), powder, insulin stimulator

同義詞:

(1S,2R,6S)-2-羟基-9-(羟甲基)-3-氧杂二环[4.3.0]壬-4,8-二烯-5-羧酸甲酯

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About This Item

經驗公式(希爾表示法):
C11H14O5
CAS號碼:
分子量::
226.23
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

product name

京尼平, ≥98% (HPLC), powder

化驗

≥98% (HPLC)

形狀

powder

溶解度

DMSO: ≥25 mg/mL
H2O: insoluble

SMILES 字串

COC(=O)C1=CO[C@@H](O)C2C1CC=C2CO

InChI

1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1

InChI 密鑰

AZKVWQKMDGGDSV-BCMRRPTOSA-N

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一般說明

京尼平是一种天然的交联剂,从栀子果实中提取。它可以防止脂质过氧化和一氧化氮的产生。京尼平保护海马神经元免受阿尔茨海默氏症淀粉样β蛋白的毒性。它具有抗炎和抗血管生成的作用。京尼平参与药物输送系统。

應用

京尼平已被用于:
  • 化学敏感性测定
  • 制备重组人(rh)- 多基因成釉细胞相关蛋白(ODAM)- 浸渍胶原凝胶和体外矿化试验
  • 京尼平凝胶制剂

生化/生理作用

京尼平以 UCP2 依赖性方式刺激胰岛素分泌(解偶联蛋白 2)。 京尼平是蛋白质、胶原蛋白、明胶和壳聚糖交联剂。

特點和優勢

该化合物在受体分类和信号转导手册的 InsR 页面上有重点介绍。如需浏览其他手册页面,请点击此处

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Using dairy ingredients to produce edible films and biodegradable packaging materials
Tomasula PM
Dairy-Derived Ingredients: Food and Nutraceutical Uses, 589-624 (2009)
Genipin-crosslinked chitosan hydrogels as biomedical and pharmaceutical aids
Muzzarelli RAA
Carbohydrate Polymers, 77(1), 1-9 (2009)
Daniel J Macaya et al.
Biomaterials, 34(14), 3591-3602 (2013-02-19)
Astrocytes can play dual roles in the response to spinal cord injury (SCI) acting as both an inhibitory barrier and a trophic support for growth axons. Therefore, migration of these cells into the defect as opposed to forming a scar
Yuanting Xu et al.
Carbohydrate polymers, 92(1), 448-454 (2012-12-12)
Biological tissues must be chemically fixed before they can be implanted in humans, due to the immediate degradation and presence of antigenicity of naturally derived tissues. To provide a crosslinking reagent which is cytocompatible and may prepare biocompatible fixed tissues
Aji P Mathew et al.
Macromolecular bioscience, 13(3), 289-298 (2012-12-12)
Bio-based fibrous nanocomposites of cellulose nanofibres and non-crosslinked/crosslinked collagen were prepared by in situ pH-induced fibrillation of collagen phase and sterilized using gamma rays at 25 KGy. Collagen phase is crosslinked using genipin, a bio-based crosslinker that introduces flexible crosslinks.

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