推薦產品
生物源
rat
品質等級
重組細胞
expressed in baculovirus infected Sf21 cells
化驗
≥97% (SDS-PAGE)
形狀
lyophilized powder
效力
0.10-10 ng/mL
分子量
~30 kDa
包裝
pkg of 10 μg
儲存條件
avoid repeated freeze/thaw cycles
技術
cell culture | mammalian: suitable
雜質
endotoxin, tested
UniProt登錄號
儲存溫度
−20°C
基因資訊
rat ... Gdnf(25453)
生化／生理作用
Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that is a member of the TGF-β superfamily. GDNF is founding member of the GDNF family of ligands, which to date include GDNF, neurturin (NTN), persephin (PSP) and artemin (ART). GDNF is a glycosylated disulfide-linked homodimeric protein of ~15 kDa. Mature rat and human GDNF share 93% sequence homology with strong species cross-reactivity. GDNF promotes survival of various neuronal cells in central and peripheral nervous systems and different stages of development including motoneurons, midbrain dopaminergic neurons, Purkinje cells, and sympathetic neurons. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes, and skeletal muscle cells. In addition, exogenously applied GDNF has been shown to rescue damaged facial motor neurons in vivo.
外觀
Lyophilized from 50 μL of a 0.2 um filtered solution in PBS, pH 7.4 with 50 ug BSA per 1 ug as a carrier protein
分析報告
The biological activity of GDNF is measured by its ability to bind to immobilized rrGFRa1/Fc in a functional ELISA.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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