推薦產品
生物源
synthetic
品質等級
形狀
powder
顏色
yellow
mp
256-256 °C
溶解度
formic acid: 50 mg/mL
抗生素活性譜
Gram-positive bacteria
parasites
作用方式
enzyme | inhibits
SMILES 字串
[O-][N+](=O)c1ccc(\C=N\N2CCOC2=O)o1
InChI
1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+
InChI 密鑰
PLHJDBGFXBMTGZ-WEVVVXLNSA-N
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相關類別
應用
呋喃唑酮是硝基呋喃衍生物,具有抗原虫和抗菌活性。呋喃唑酮与细菌 DNA 结合,从而导致单胺氧化酶逐渐受到抑制。用于治疗厌食和拮抗家禽对硫胺素的利用 。呋喃唑酮增加鸡心肌细胞中对毒胡萝卜素敏感的 Ca 2+-atp 酶 。
生化/生理作用
呋喃唑酮及其产生的自由基,可能与 DNA 结合并诱导交联。细菌 DNA 对本药特别敏感,从而导致细菌染色体的高水平突变(转换和颠换)。其作用机制使耐药生物体的发展最小化。呋喃唑酮是一种单胺氧化酶 (MAO) 抑制剂,用作 DNA 链间交联剂。
訊號詞
Warning
危險聲明
危險分類
Repr. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
個人防護裝備
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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