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Merck
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重要文件

F3685

Sigma-Aldrich

Fibroblast Growth Factor-Basic, human

≥97% (SDS-PAGE), recombinant, expressed in E. coli, carrier free, suitable for cell culture

同義詞:

FGB-b, FGF-2, HBGF-2, HBGH-2, Prostatropin, bFGF

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.77

product name

Fibroblast Growth Factor-Basic, FGF-Basic, from human, recombinant, expressed in E. coli, carrier free

生物源

human

品質等級

重組細胞

expressed in E. coli

化驗

≥97% (SDS-PAGE)

形狀

lyophilized powder

效力

<1 ng/mL Biological Activity EC50

分子量

16.0 kDa

包裝

pkg of 4X25 μg
pkg of 25 μg

儲存條件

avoid repeated freeze/thaw cycles

顏色

white to faint yellow cast

溶解度

water: soluble 0.025 mg, clear, colorless to faintly yellow

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... FGF2(2247)

一般說明

Since FGF-Basic is found in a variety of organs, acts on a wide range of cell types, and has multifunctional actions, it has acquired numerous synonyms, including heparin-binding growth factor (class II or beta), eye-derived growth factor I, cartilage-derived growth factor, and astroglial growth factor II5. Purified bovine and human FGF-basic differ by 3 amino acids in sequence3, and are biologically and immunologically cross-reactive.

引用

1. Gospodarowicz, D., Localization of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth. Nature, 249, 123-127 (1974).
2. Gospodarowicz, D. et al., Structural characterization and biological functions of fibroblast growth factor. Endo. Rev., 8, 95-114 (1987).
3. Esch, F. et al., Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proc. Natl. Acad. Sci. USA, 82, 6507-6511 (1985).
4. Neufeld, G., and Gospodarowicz, D., Basic and acidic fibroblast growth factors interact with the same cell surface receptors. J. Biol. Chem., 261, 5631-5637 (1986).
5. Lobb, R.R. et al., Purification of heparin-binding growth factors. Anal. Biochem., 154, 1-14 (1986).
6. Abraham, J.A., Human basic fibroblast growth factor: nucleotide sequence and genomic organization. EMBO J., 5, 2523- 2528 (1986).

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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