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一般說明
羧酸酯酶1（CE1）是大型多基因羧酸酯酶 α,β水解酶家族的成员。它主要在肝脏中表达。CE1 包括一个 αβ 结构域、一个中心催化结构域和一个调控结构域。
應用
人羧酸酯酶 1 亚型 c 已被用作贻贝羧酸酯酶活性的参考标准，用于比较底物特异性和抑制研究。它还被用作商业重组蛋白，用于基于环境化学的抑制研究的方法验证。
生化／生理作用
羧酸酯酶负责水解含有酯键和酰胺键的药物，例如可卡因和海洛因。它们还水解长链脂肪酸酯和硫酯。羧酸酯酶 1（CE1）催化胆固醇和脂肪酸形成胆固醇酯。通过酯交换反应，CE1 还介导脂肪酸乙酯（FAEE）的产生。它还水解芳族和脂族酯，优先于小的醇基和大的酰基。CE1 代谢药物酯类和酰胺类氨基甲酸酯。它参与环境毒物和致癌物的解毒，并可用于评估前药的药代动力学研究。
物理性質
该产品的体积为0.5 mL。
單位定義
一个单位是指在pH 7.4、37℃下，每分钟水解1纳摩尔4-硝基苯基乙酸酯所需的酶量
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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The common sole, Solea solea (Linneus, 1758), and the Senegalese sole, Solea senegalensis (Kaup, 1858), are two important commercial species that coexist in the NW Mediterranean. In order to assess the species' ability to respond to chemical insults, a comparison
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