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Key Documents

D6382

Sigma-Aldrich

N,N-二甲基甘氨酸 盐酸盐

≥98%, suitable for ligand binding assays

同義詞:

N,N-二甲基氨基乙酸 盐酸盐

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About This Item

線性公式:
(CH3)2NCH2COOH · HCl
CAS號碼:
分子量::
139.58
Beilstein:
3910578
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.26

product name

N,N-二甲基甘氨酸 盐酸盐,

化驗

≥98%

形狀

powder

技術

ligand binding assay: suitable

顏色

white

mp

189-194 °C (lit.)

SMILES 字串

Cl.CN(C)CC(O)=O

InChI

1S/C4H9NO2.ClH/c1-5(2)3-4(6)7;/h3H2,1-2H3,(H,6,7);1H

InChI 密鑰

FKASAVXZZLJTNX-UHFFFAOYSA-N

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生化/生理作用

N,N-二甲基甘氨酸(DMG)是一种天然的N-甲基化甘氨酸,它被用于与其他N-甲基化甘氨酸(如肌氨酸和 βine)的比较分析。N,N-二甲基甘氨酸倍用于开发基于甘氨酸的离子液体和乳化剂。N,N-二甲基甘氨酸可能被用作COPD患者蛋白质降解的生物标志物。DMG被用作底物,以鉴定、区分和表征氨基酸甲基转移酶。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Characterization of osmolyte βine synthesizing sarcosine dimethylglycineN-methyltransferase from Methanohalophilus portucalensis.
Chen SY, Lai MC, Lai SJ, Lee YC.
Applied Microbiology, 191, 735-743 (2009)
Jing-Fang Zhu et al.
The journal of physical chemistry. B, 116(1), 113-119 (2011-12-14)
The experimental and theoretical enthalpies of formation of several structural-similar glycine-based sulfate/bisulfate amino acid ionic liquids including glycine sulfate (Gly(2)SO(4), 1), glycine bisulfate (GlyHSO(4), 2), N,N-dimethylglycine sulfate ([DMGly](2)SO(4), 3), N,N-dimethylglycine bisulfate ([DMGly]HSO(4), 4), N,N-dimethylglycine methyl ester sulfate ([DMGlyC(1)](2)SO(4), 5), N,N-dimethylglycine
A J Hoorn
Mutation research, 222(4), 343-350 (1989-04-01)
Dimethylglycine (DMG) and the chemically related amino acids glycine, sarcosine (monomethylglycine) and betaine (trimethylglycine) were tested in Salmonella typhimurium strain TA100 after treatment with sodium nitrite under acidic conditions using a modified Ames Salmonella/microsome assay as reported by Colman et
Baljit K Ubhi et al.
The European respiratory journal, 40(2), 345-355 (2011-12-21)
There is a paucity of biomarkers for chronic obstructive pulmonary disease (COPD). Metabolomics were applied to a defined COPD patient cohort from the ECLIPSE study (Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points). Results were correlated with accepted biomarkers
Michael Lever et al.
PloS one, 7(5), e37883-e37883 (2012-06-01)
Betaine insufficiency is associated with unfavourable vascular risk profiles in metabolic syndrome patients. We investigated associations between betaine insufficiency and secondary events in acute coronary syndrome patients. Plasma (531) and urine (415) samples were collected four months after discharge following

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