跳轉至內容
Merck
全部照片(1)

Key Documents

D1414

Sigma-Aldrich

氟哌利多

同義詞:

1-[1-[3-(p-Fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-2-benzimidazolinone

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C22H22FN3O2
CAS號碼:
分子量::
379.43
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.77

形狀

powder

起源

Johnson & Johnson

儲存溫度

2-8°C

SMILES 字串

Fc1ccc(cc1)C(=O)CCCN2CCC(=CC2)N3C(=O)Nc4ccccc34

InChI

1S/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28)

InChI 密鑰

RMEDXOLNCUSCGS-UHFFFAOYSA-N

尋找類似的產品? 前往 產品比較指南

生化/生理作用

D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic.
Droperidol is a potent antagonist of dopamine subtype 2 receptor. It is an antipsychotic, which is used to treat acute behavioral anomalies. It helps to manage postoperative nausea and vomiting.

特點和優勢

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

The safety and effectiveness of droperidol for sedation of acute behavioral disturbance in the emergency department
Calver L, et al.
Annals of Emergency Medicine, 66(3), 230-238 (2015)
A Hamik et al.
Cancer chemotherapy and pharmacology, 24(5), 307-310 (1989-01-01)
The affinities of 11 drugs for both dopamine D2 and 5-hydroxytryptamine3 (5-HT3) receptor sites were determined in brain membranes. The five "traditional" antiemetics (chlorpromazine, prochlorperazine, droperidol, fluphenazine, and domperidone) displayed high affinity (less than 20 nM) for dopamine D2 receptors
Gregory A Nuttall et al.
Anesthesiology, 118(2), 382-386 (2013-01-08)
The Food and Drug Administration issued a black box warning regarding the use of droperidol and the potential for torsade de pointes. The primary objective of this retrospective study was to determine if low-dose (0.625 mg) droperidol administration was associated
Christopher Spevak et al.
Pain medicine (Malden, Mass.), 13(8), 1072-1080 (2012-06-12)
The most feared drug-induced complication is fatal cardiac arrest. Torsades de pointes (TdP) is a polymorphic ventricular tachycardia occurring in the setting of a QT interval prolongation and is the most frequent type of drug-induced pro-arrhythmia. The most common mechanism
Esther W Chan et al.
Annals of emergency medicine, 61(1), 72-81 (2012-09-18)
Parenteral benzodiazepines or antipsychotics are often used to manage acute agitation in emergency department (ED) settings in which alternative strategies have failed or are not feasible. There are scant data comparing parenteral medication regimens. We aim to determine the efficacy

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務