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T4009

Sigma-Aldrich

牛磺胆酸 钠盐 水合物

≥95% (HPLC)

同義詞:

2-[(3α,7α,12α-三羟基-24-氧基-5β-胆烷-24-基)氨基]乙磺酸, 3α,7α,12α-三羟基-5β-胆烷-24-酸N-(2-磺乙基)酰胺, 牛胆酸钠 水合物

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About This Item

經驗公式（希爾表示法）:
C26H44NNaO7S · xH2O
CAS號碼:
345909-26-4
分子量：:
537.68 (anhydrous basis)
EC號碼:
205-653-7
MDL號碼:
MFCD00150819
分類程式碼代碼:
12161900
PubChem物質ID:
24900186
NACRES:
NA.25

生物源

synthetic (organic)

品質等級

200

描述

anionic

化驗

≥95% (HPLC)

形狀

powder

分子量

micellar avg mol wt 2100

凝集数

4

CMC

3-11 mM (20-25°C)

官能基

sulfonic acid

運輸包裝

ambient

儲存溫度

room temp

SMILES 字串

[Na+].[H]O[H].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS([O-])(=O)=O

InChI

1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1

InChI 密鑰

RDAJAQDLEFHVNR-NEMAEHQESA-M

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相關類別

一般說明

巯基乙酸钠水合物是一种胆汁酸，有洗涤剂作用。

應用

巯基乙酸钠水合物被用来评估植物纤维组织对胆汁酸和盐的吸收度。 它在一项研究中被用来检测血清和空肠液中的共轭和非共轭胆汁酸。
阴离子洗涤剂用于蛋白质溶解。

生化／生理作用

非硫化胆盐，是胆盐排出泵/Pgp（BSEP/spgp)姐妹，Na(+)/牛磺胆酸协同转运蛋白和MRP3进入肝脏系统的生理性转运底物。

準備報告

从胆酸合成

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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Joseph J Orsini et al.
Clinica chimica acta; international journal of clinical chemistry, 413(15-16), 1270-1273 (2012-05-03)
We sought to modify a previously published tandem mass spectrometry method of screening for 5 lysosomal storage disorders (LSDs) in order to make it better suited for high-throughput newborn screening. Two 3-mm dried blood spot (DBS) punches were incubated, each
Studies on the adsorption of bile salts to non-absorbed components of diet.
M A Eastwood et al.
Biochimica et biophysica acta, 152(1), 165-173 (1968-01-10)
A Tangerman et al.
Clinica chimica acta; international journal of clinical chemistry, 159(2), 123-132 (1986-09-15)
A reliable method is described for the determination of conjugated and unconjugated bile acids in serum and jejunal fluid. Bile acids are extracted using reverse-phase octadecylsilane bonded silica cartridges and are separated into their unconjugated and conjugated fractions using the
Theresa D Ho et al.
Infection and immunity, 82(6), 2345-2355 (2014-03-26)
Clostridium difficile is a clinically important pathogen and the most common cause of hospital-acquired infectious diarrhea. Expression of the C. difficile gene csfV, which encodes σ(V), an extracytoplasmic function σ factor, is induced by lysozyme, which damages the peptidoglycan of
Studies on the Antibacterial Properties of the Bile Acids and some Compounds Derived from Cholanic Acid
M. Stacey and M. Webb
Proc. Royal Soc. Lond. B., 134, 523-523 (1947)
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