C240

8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt

≥98% (HPLC), solid

• 同義詞: Rp-8-CPT-cGMPS, Rp-8-[(4-Chlorophenyl)thio]-cGMPS triethylammonium salt, Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3′,5′-hydrogen phosphorothioate triethylammonium salt
• 經驗公式（希爾表示法）: C₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N
• CAS號碼: 276696-61-8
• 分子量：: 605.07
• MDL號碼: MFCD04037247
• 分類程式碼代碼: 41106305
• PubChem物質ID: 329775000
• NACRES: NA.77

屬性

• 生物源: synthetic
• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: solid
• 顏色: white
• 溶解度: H₂O: 5 mg/mL
• 儲存溫度: −20°C
• SMILES 字串: CCN(CC)CC.NC1=Nc2c(nc(Sc3ccc(Cl)cc3)n2[C@@H]4O[C@@H]5CO[P@@](O)(=S)O[C@H]5[C@H]4O)C(=O)N1
• InChI: 1S/C16H15ClN5O6PS2.C6H15N/c17-6-1-3-7(4-2-6)31-16-19-9-12(20-15(18)21-13(9)24)22(16)14-10(23)11-8(27-14)5-26-29(25,30)28-11;1-4-7(5-2)6-3/h1-4,8,10-11,14,23H,5H2,(H,25,30)(H3,18,20,21,24);4-6H2,1-3H3/t8-,10-,11-,14-,29-;/m1./s1
• InChI 密鑰: KVOYZBYGWGWWTD-TXBWCVORSA-N

描述

生化／生理作用

Rp-8-CPT-cGMP is a potent inhibitor of protein kinase G Ia, Ib, and type II.

特點和優勢

This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

聯結

8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt is more cell permeable than Rp-cGMPS triethylamine.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)