推薦產品
一般說明
化合物48/80,是一种N-甲基p-甲氧基苯乙基胺和甲醛缩合产物。
應用
48/80化合物可用来:
- 刺激血细胞释放组胺,从而通过ELISA和流式细胞仪测定
- 诱发肥大细胞脱粒
- 诱发小鼠过敏性活动、皮炎、瘙痒和炎症
生化/生理作用
化合物48/80是一种低血压药,促进组胺释放。C 48/80降低了 Styela plicata血细胞的吞噬能力。C 48/80 促进肥大细胞脱粒。它抑制钙调蛋白,磷脂酶C,内质网(ER)Ca2+磷酸酶和激活G蛋白。
準備報告
N-甲基-p-甲氧基苯乙基胺和甲醛缩合产物。
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Differential activation of the PI 3-kinase effectors AKT/PKB and p70 S6 kinase by compound 48/80 is mediated by PKC alpha
Cellular Signalling, 19(2), 321-329 (2007)
Signal transduction and targeted therapy, 6(1), 428-428 (2021-12-19)
SARS-CoV-2 infection-induced hyper-inflammation links to the acute lung injury and COVID-19 severity. Identifying the primary mediators that initiate the uncontrolled hypercytokinemia is essential for treatments. Mast cells (MCs) are strategically located at the mucosa and beneficially or detrimentally regulate immune
European journal of pharmacology, 115(2-3), 163-170 (1985-09-24)
Compound 48/80 and 14C-labeled compound 48/80 were synthesized, and fractionated by thin-layer chromatography into 14 components (A-N) with various histamine releasing activities and different Ca2+ requirements for their actions. The histamine release induced from rat mast cells in vitro by
The Journal of investigative dermatology, 138(6), 1391-1399 (2017-12-31)
Cooling or the application of mentholated liniments to the skin has been used to treat itch for centuries, yet remarkably little is known about how counter-stimuli such as these induce itch relief. Indeed, there is no clear consensus in the
Development of a short-term canine full-thickness skin organ culture method under serum-free conditions
American Journal of Animal and Veterinary Sciences, 11(2), 61-69 (2016)
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務