推薦產品
產品名稱
辣椒平, ≥98% (HPLC), solid
品質等級
化驗
≥98% (HPLC)
形狀
solid
顏色
off-white
溶解度
DMSO: >10 mg/mL, clear
儲存溫度
2-8°C
SMILES 字串
Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc3ccc(Cl)cc3
InChI
1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25)
InChI 密鑰
DRCMAZOSEIMCHM-UHFFFAOYSA-N
基因資訊
human ... TRPV1(7442) , TRPV4(59341)
rat ... Trpv1(83810)
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應用
辣椒平作为瞬时受体电位香草醛-1(TRPV1)拮抗剂的应用实例：
- 研究其对辣椒素诱导的胞外信号调节激酶(ERK)磷酸化的影响作用
- 研究TRPV1在大鼠伤害感受器中枢神经末梢的作用
- 公牛精子中TRPV1的功能表征
生化／生理作用
辣椒平(Capsazepine)是人工合成的辣椒素类似物和瞬时受体电位香草醛-1(TRPV1)拮抗剂。在多种癌症中具有抗增殖和抗癌作用，包括口腔鳞状细胞癌、非小细胞肺癌(NSCLC)、乳腺癌和前列腺癌细胞株（HSC-3、H460、MDA-231和PC-3）。辣椒平可恢复在内毒素血症中受损的肺机能，可作为急性肺损伤(ALI)的潜在治疗药物。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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