推薦產品
品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to off-white
溶解度
DMSO: >20 mg/mL
儲存溫度
2-8°C
SMILES 字串
ClC1=C(S(N(C(C)C)CCNC(C)C)(=O)=O)C=CC(Cl)=C1
InChI
1S/C14H22Cl2N2O2S/c1-10(2)17-7-8-18(11(3)4)21(19,20)14-6-5-12(15)9-13(14)16/h5-6,9-11,17H,7-8H2,1-4H3
InChI 密鑰
IHYZMEAZAIFMTN-UHFFFAOYSA-N
應用
RN-1734 has been used as a transient receptor potential vanilloid 4 (TRPV4) blocker to study its effects on differentiation of a corneal epithelial cell model, RCE1(5T5) cells.
生化/生理作用
RN-1734 is a selective TRPV4 antagonist.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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TRPV4 (transient receptor potential vanilloid 4) is a cation channel activated by hypotonicity, moderate heat, or shear stress. We describe the expression of TRPV4 during the differentiation of a corneal epithelial cell model, RCE1(5T5) cells. TRPV4 is a late differentiation
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Journal of Cellular Physiology, 232(7), 1794-1807 (2017)
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