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Merck
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重要文件

B9806

Sigma-Aldrich

肝素−生物素 钠盐

≥97%

同義詞:

肝素-生物素偶联物

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About This Item

MDL號碼:
分類程式碼代碼:
12352201
eCl@ss:
34058011
NACRES:
NA.25

共軛

biotin conjugate

品質等級

化驗

≥97%

形狀

solid

分子量

~15000 Da

溶解度

H2O: soluble 1 mg/mL, clear, colorless

儲存溫度

2-8°C

應用

肝素-生物素用于转染研究,用于开发自组装的三链体,例如聚酰胺基胺树枝状聚合物和DNA(PAMAM/DNA)肝素-生物素三链体,用于靶向基因转运,并改善转染。该三链体可用于固定蛋白质如乳铁蛋白和溶菌酶以及核酸。

其他說明

猪肠粘膜肝素偶联的生物素

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Xue-Qing Zhang et al.
Bioconjugate chemistry, 18(6), 2068-2076 (2007-09-13)
We report on the preparation and characterization of poly(D, L-lactide-co-glycolide) (PLGA) microparticles with surface-conjugated polyamidoamine (PAMAM) dendrimers of varying generations. The buffering capacity and zeta-potential of the PLGA PAMAM microparticles increased with increasing generation level of the PAMAM dendrimer conjugated.
Nan Liu et al.
Die Pharmazie, 67(2), 174-181 (2012-04-20)
The efficiency and safety of gene delivery vectors were important factors for gene therapy. To enhance gene transfection efficiency and to incorporate biocompatible components to the polyamidoamine (PAMAM) dendrimer mediated gene delivery systems, human serum albumin (HSA) was introduced to
Dzmitry Shcharbin et al.
Journal of controlled release : official journal of the Controlled Release Society, 141(2), 110-127 (2009-10-10)
This paper reviews different techniques for analyzing the transfection efficiencies and cytotoxicities of dendriplexes-complexes of nucleic acids with dendrimers. Analysis shows that three plasmids are mainly used in transfection experiments: plasmid DNA encoding luciferase from the firefly Photinus pyralis, beta-galactosidase
Kelly M Kitchens et al.
Advanced drug delivery reviews, 57(15), 2163-2176 (2005-11-18)
This article summarizes our efforts to evaluate the potential of poly (amidoamine) (PAMAM) dendrimers as carriers for oral drug delivery. Specifically, the permeability of a series of cationic PAMAM-NH2 (G0-G4) dendrimers across Caco-2 cell monolayers was evaluated as a function
Qiao Zhang et al.
Bioconjugate chemistry, 21(11), 2086-2092 (2010-10-12)
To improve transfection efficiency and to incorporate target ligands to the gene delivery systems, heparin and heparin-biotin were introduced to complexes of polyamidoamine dendrimer and DNA (PAMAM/DNA) via electrostatic interactions to form self-assembled PAMAM/DNA/heparin and PAMAM/DNA/heparin-biotin terplexes, respectively. The self-assembled

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