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Key Documents

MAB570

Sigma-Aldrich

Anti-Heparin Antibody, clone A7.10

clone A7.10, Chemicon®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

A7.10, monoclonal

物種活性

mouse

應無反應活性

pig

製造商/商標名

Chemicon®

技術

ELISA: suitable
radioimmunoassay: suitable

同型

IgG2b

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

mouse ... Hdgf(15191)

特異性

Reacts with mouse heparin. Cross reacts with dextran sulfate by EIA. Also shows some cross reactivity to DNA and heparan sulfate.

應用

Detect Heparin using this Anti-Heparin Antibody, clone A7.10 validated for use in ELISA, RIA.
EIA/RIA (kd by liquid phase RIA for heparin is approximately

1.0 x 10-11 M.) Suggested concentration 1-10 μg/mL.

Inhibits the formation of heparin accelerated thrombin-antithrombin complex formation in vitro.

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

外觀

Format: Purified
Purified immunoglobulin. Liquid in 0.02M PB + 0.25M NaCl, pH 7.6 with 0.1% Sodium azide.

儲存和穩定性

Maintain at 2-8°C.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Autoimmune MRL mice express high-affinity IgG2b monoclonal autoantibodies to heparin.
Fillit, H, et al.
Clinical Immunology and Immunopathology, 81, 62-67 (1996)
J Qiu et al.
Virology, 269(1), 137-147 (2000-03-22)
Recently heparan sulfate was proposed as the host cell receptor for the dependovirus, adeno-associated virus type 2 (AAV2). We show that although heparan sulfate on the cell surface may contribute to the binding of AAV2 to permissive cells, the amount
E Ortega-Barria et al.
The Journal of biological chemistry, 274(3), 1267-1276 (1999-01-09)
Toxoplasma gondii is one of the most widespread parasites of humans and animals. The parasite has a remarkable ability to invade a broad range of cells within its mammalian hosts by mechanisms that are poorly understood at the molecular level.

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