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About This Item
經驗公式(希爾表示法):
C4H12NaNO7P2 · 3 H2O
CAS號碼:
分子量::
325.12
MDL號碼:
分類程式碼代碼:
41106300
PubChem物質ID:
NACRES:
NA.77
推薦產品
化驗
≥97% (NMR)
形狀
powder
顏色
white
溶解度
water, double-distilled: 10 mg/mL
儲存溫度
−20°C
SMILES 字串
[Na+].[H]O[H].[H]O[H].[H]O[H].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O
InChI
1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1
InChI 密鑰
DCSBSVSZJRSITC-UHFFFAOYSA-M
基因資訊
human ... FDPS(2224)
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應用
阿仑膦酸钠三水合物已被用于:钛植入物的磷酸钙纳米颗粒(nCaP)二膦酸盐(BP)涂层并用于分析其成骨能力 从老年骨质疏松症患者和健康人群中分离的人骨髓基质细胞(hBMSC)的成骨分化 处理成骨细胞祖细胞和成骨细胞并通过传统测定和简单的数字图象分析研究其对成骨细胞行为的影响
生化/生理作用
阿仑膦酸钠三水合物是一种骨吸收抑制剂;法尼基二磷酸合成酶抑制剂 (IC 50 = 460 nM);CD45 蛋白酪氨酸磷酸酶抑制剂。
阿伦膦酸盐是一种含氮二膦酸盐,可阻断甲羟戊酸途径 并限制破骨功能和活性。阿仑膦酸钠三水合物是一种骨吸收抑制剂、法尼基二磷酸合成酶抑制剂和 CD45 蛋白酪氨酸磷酸酶抑制剂。
儲存和穩定性
重溶后,建议在-20°C下分装冻存。储备液在-20°C条件下可稳定保存6个月。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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