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Merck
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重要文件

A0972

Sigma-Aldrich

Apolipoprotein A-II 来源于人类血浆

≥95% (SDS-PAGE), buffered aqueous solution

同義詞:

Apo A-II

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

human plasma

品質等級

化驗

≥95% (SDS-PAGE)

形狀

buffered aqueous solution

分子量

17.38 kDa

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

基因資訊

human ... APOA2(336)

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一般說明

Forms dimers in aqueous solutions with an association constant of 5 × 104 M-1. The association is accompanied by an enhancement of ~35% in α-helical content.

應用

Apo A-II constitutes ~20% of the protein moiety of high density lipoprotein (HDL).

生化/生理作用

Unlike Apo A-I, Apo A-II possesses no activating properties for lectin-cholesterol acyltransferase (LCAT). Furthermore, it was found that Apo A-II inhibits the activation of LCAT by Apo A-I.

外觀

Solution in 10 mM ammonium bicarbonate.

免責聲明

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Effect of disulfide cleavage on the molecular weight of one of the major polypeptides of human serum high density lipoprotein.
A M. Scanu et al.
FEBS letters, 18(2), 305-307 (1971-11-01)
Cécile Voisset et al.
The Journal of biological chemistry, 280(9), 7793-7799 (2005-01-06)
The scavenger receptor class B type I (SR-BI) has recently been shown to interact with hepatitis C virus (HCV) envelope glycoprotein E2, suggesting that it might be involved at some step of HCV entry into host cells. However, due to

文章

Since cholesterol is a water-insoluble molecule it must be packaged for transport within the plasma. The particles that package cholesterol, cholesteryl esters, and triglycerides for transport, are called lipoproteins.

Since cholesterol is a water-insoluble molecule it must be packaged for transport within the plasma. The particles that package cholesterol, cholesteryl esters, and triglycerides for transport, are called lipoproteins.

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