451M-1

h-Caldesmon (hHCD) Mouse Monoclonal Antibody

• 分類程式碼代碼: 12352203

屬性

• 生物源: mouse
• 品質等級: 100; 500
• 共軛: unconjugated
• 抗體表格: diluted ascites fluid
• 抗體產品種類: primary antibodies
• 無性繁殖: hHCD, monoclonal
• 描述: For In Vitro Diagnostic Use in Select Regions
• 形狀: buffered aqueous solution
• 物種活性: human
• 包裝: vial of 0.1 mL concentrate (451M-14); vial of 0.1 mL concentrate Research Use Only (451M-14-RUO); vial of 0.5 mL concentrate (451M-15); vial of 1.0 mL concentrate (451M-16); vial of 1.0 mL concentrate Research Use Only (451M-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (451M-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (451M-17); vial of 7.0 mL pre-dilute ready-to-use (451M-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (451M-18-RUO)
• 製造商／商標名: Cell Marque^™
• 技術: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 (concentrated)
• 同型: IgG1
• 控制: bladder, colon, leiomyoma, smooth muscle tumors, stomach
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 視覺化: cytoplasmic

描述

一般說明

Caldesmon is a protein that facilitates the regulation of cellular contraction through complexing with calmodulin, tropomyosin, and actin. Its high molecular weight isoform (h-caldesmon) has been identified to have restricted expression in visceral and vascular smooth muscle cells. In particular, strong expression of h-caldesmon has been observed in non-neoplastic uterine myometrium while being entirely absent in the endometrial layer. In spindle cell tumor pathology, overlapping immunohistochemical staining profiles between smooth muscle cells and myofibroblastic cells has not allowed for reliable identification of true smooth muscle tumors. Immunohistochemical detection of h-caldesmon has been demonstrated to aid in the distinguishing smooth muscle tumors, such as leiomyoma and leiomyosarcoma from myofibroblastic lesions, such as inflammatory myofibroblastic tumors and fibromatoses.

品質

IVD

IVD

IVD

RUO

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

準備報告

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其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2