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重要文件

283M-1

Sigma-Aldrich

HBME-1 (HBME-1) Mouse Monoclonal Antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
無性繁殖:
HBME-1, monoclonal
application:
IHC (p)
物種活性:
human
技術:
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
citations:
6

生物源

mouse

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

HBME-1, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (283M-14)
vial of 0.5 mL concentrate (283M-15)
bottle of 1.0 mL predilute (283M-17)
vial of 1.0 mL concentrate (283M-16)
bottle of 7.0 mL predilute (283M-18)

製造商/商標名

Cell Marque

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

同型

IgMκ

控制

mesothelioma

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

cytoplasmic, membranous

一般說明

Hector Battifora mesothelial-1 (HBME-1) is a membrane antigen that exists in the microvilli ofmesothelial cells and other epithelial cells. Anti-HBME-1 labels thyroid papillary carcinomaand follicular carcinoma but not normal thyroid making it a valuable marker for distinguishingthyroid malignancies from benign thyroid lesions. It has also been demonstrated to labelmesothelial cells, both benign and malignant (malignant mesothelioma), and thus can aid inthe identification of mesothelioma.

品質


IVD

IVD

IVD

RUO

聯結

HBME-1 Positive Control Slides, Product No. 283S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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J E Barroeta et al.
Endocrine pathology, 17(3), 225-234 (2007-02-20)
Several immunohistochemical markers have been used to aid in the diagnosis of follicular-derived lesions of the thyroid (FDLT). In this study we analyze the diagnostic efficacy of an immunopanel of antibodies to cytokeratin-19 (CK19), galectin-3 (GAL-3), HBME-1, anti-MAP kinase (ERK)
Daniela Cabibi et al.
Thyroid : official journal of the American Thyroid Association, 17(7), 603-607 (2007-08-19)
To verify whether immunohistochemistry might be useful in the distinction between a true laterocervical metastasis of an undetected thyroid carcinoma and a primary tumor outside the gland. Galectin-3, cytokeratin 19, and HBME-1 were assessed in six cases (group A) of
A Coli et al.
Journal of experimental & clinical cancer research : CR, 26(2), 221-227 (2007-08-30)
Ninety-six thyroid lesions were immunohistochemically evaluated for HBME-1 and Galectin-3 expression including nodules with cytological atypia, the latter defined as nuclear features suggestive but not diagnostic of papillary thyroid carcinoma. Thirty nodules with cytological atypia, 49 papillary thyroid carcinomas (PTCs)
Liborio Torregrossa et al.
Human pathology, 38(10), 1482-1488 (2007-06-29)
The histologic diagnosis of the follicular variant of papillary thyroid carcinoma (FVPTC) may be troublesome, especially in its encapsulated form. We evaluated the expression of galectin-3 (gal-3) and Hector Battifora mesothelial cell (HBME-1) in 200 formalin-fixed thyroid tissues with diagnosis

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