推薦產品
生物源
mouse
品質等級
100
500
共軛
unconjugated
抗體表格
culture supernatant
抗體產品種類
primary antibodies
無性繁殖
1G12, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (261M-94)
vial of 0.5 mL concentrate (261M-95)
bottle of 1.0 mL predilute (261M-97)
vial of 1.0 mL concentrate (261M-96)
bottle of 7.0 mL predilute (261M-98)
製造商／商標名
Cell Marque™
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
同型
IgG1
控制
hepatocellular carcinoma (HCC)
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
cytoplasmic
基因資訊
human ... GPC3(2719)
一般說明
磷脂酰肌醇蛋白聚糖3（GPC3）是一种膜结合硫酸肝素蛋白聚糖，可参与细胞生长和分化。GPC3的表达见于大多数肝细胞癌（HCC），但是在非肿瘤肝组织中非常少见，这使其成为有用的HCC标记物。此外，这种标记物在许多卵黄囊瘤中表达。
品質
 IVD |  IVD |  IVD | RUO |
聯結
磷脂酰肌醇聚糖-3阳性对照玻片，产品编号261S，可用于免疫组化（福尔马林固定、石蜡包埋的切片）。
外觀
溶于Tris缓冲液中的溶液（pH 7.3-7.7），含1％BSA和 <0.1％叠氮化钠
準備報告
下载针对您的产品批次和规格的使用说明书(IFU)注意：该过程需要可在包装或产品标签上找到的密钥代码。
其他說明
有关技术服务，请联系： 800-665-7284或电子邮件：service@cellmarque.com
法律資訊
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Dina Kandil et al.
Cancer, 111(5), 316-322 (2007-09-01)
Glypican-3 (GPC3) is a heparan sulfate proteoglycan which is elevated in the serum of patients with hepatocellular carcinoma (HCC), but not in healthy blood donors, or patients with benign liver disease. GPC3 immunohistochemistry (IHC) is a promising marker of HCC
Wanda M P Coston et al.
The American journal of surgical pathology, 32(3), 433-444 (2008-02-28)
Distinguishing a well-differentiated hepatocellular carcinoma (HCC) from normal and cirrhotic liver tissue or benign liver nodules, such as hepatic adenoma (HA) and focal nodular hyperplasia (FNH), may be very difficult in some cases, particularly in small needle core biopsies. We
Dina H Kandil et al.
Advances in anatomic pathology, 16(2), 125-129 (2009-06-25)
Glypican-3 (GPC3) is a heparan sulfate proteoglycan that plays an important role in cell growth and differentiation. GPC3 function is tissue dependent. In some tissues, GPC3 acts as a tumor suppressor gene, whereas in others, it acts as an oncofetal
Debra L Zynger et al.
The American journal of surgical pathology, 30(12), 1570-1575 (2006-11-24)
Glypican 3 (GPC3), a membrane-bound heparin sulfate proteoglycan, may play a role in promoting embryonic cell growth and differentiation. GPC3 is mutated in Simpson-Golabi-Behmel syndrome, characterized by tissue overgrowth and an increased risk of embryonal malignancies. Recently, GPC3 was reported
Mariana Capurro et al.
Gastroenterology, 125(1), 89-97 (2003-07-10)
Early detection of hepatocellular carcinoma (HCC) is critical for successful treatment. However, the differential diagnosis between HCC and benign hepatic lesions is sometimes difficult and new biochemical markers for HCC are required. It has been reported that glypican-3 (GPC3) messenger
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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