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Merck
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重要文件

375810

Sigma-Aldrich

高碘酸

ACS reagent, 99%

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About This Item

經驗公式(希爾表示法):
H5IO6
CAS號碼:
分子量::
227.94
EC號碼:
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.21

等級

ACS reagent

品質等級

化驗

99%
99.0-101.0% (ACS specification)

形狀

powder or crystals

反應適用性

reaction type: C-H Activation
reagent type: catalyst
reagent type: oxidant

雜質

≤0.01% insolubles
≤0.01% other halogens

燃燒殘留物

≤0.01%

mp

122 °C (lit.)

溶解度

water: soluble

負離子痕跡

sulfate (SO42-): ≤0.01%

正離子痕跡

Fe: ≤0.003%
heavy metals: ≤0.005%

應用

histology

SMILES 字串

OI(O)(O)(O)(O)=O

InChI

1S/H5IO6/c2-1(3,4,5,6)7/h(H5,2,3,4,5,6,7)

InChI 密鑰

TWLXDPFBEPBAQB-UHFFFAOYSA-N

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相關類別

一般說明

Periodic acid is an inorganic acid commonly used as an oxidizing agent. Periodic acid oxidation is one of the steps in the periodate-resorcinol assay, used in the determination of sialic acid. Periodic acid reacts with 1,2 glycol linkage of carbohydrates to form aldehydes which can be stained by Schiff′s reagent. Therefore periodic-acid-Schiff′s reagent (PAS) is used in histochemistry to determine carbohydrates in tissue sections.

應用

Periodic acid may be used in the following reactions:
  • Oxidation of alcohols to ketones and aldehydes.
  • Oxidation hydroxylamine derivatives.
  • Oxidation of arenes to quinones.
  • Deprotection of the dithio- and oxathio-derivatives.
  • Oxidative degradation of epoxidized natural rubber (ENR).
  • Oxidation of urazoles and bis-urazoles to triazolinediones.
  • Oxidative cleavage of glucosazone.

訊號詞

Danger

危險分類

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Ox. Sol. 1 - Skin Corr. 1B - STOT RE 1 Oral

標靶器官

Thyroid

儲存類別代碼

5.1A - Strongly oxidizing hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Periodic Acid Oxidation.
Jackson EL.
Organic Reactions, 341-375 null
Carbohydrate histochemistry studied by acetylation techniques: I. Periodic acid methods.
McManus JFA and Cason JE.
The Journal of Experimental Medicine, 91(6), 651-651 (1950)
Histological and histochemical uses of periodic acid.
J F A McMANUS
Stain technology, 23(3), 99-108 (1948-07-01)
The sialic acids. XI. A periodate-resorcinol method for the quantitative estimation of free sialic acids and their glycosides.
G W Jourdian et al.
The Journal of biological chemistry, 246(2), 430-435 (1971-01-25)
The first report on the catalytic oxidation of urazoles to their corresponding triazolinediones via in situ catalytic generation of Br+ using periodic acid or oxone/KBr system.
Zolfigol MA, et al.
J. Mol. Catal. A: Chem., 270(1), 219-224 (2007)

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