8.22288

Periodic acid

for synthesis

• 同義詞: Periodic acid
• 經驗公式（希爾表示法）: H₅IO₆
• CAS號碼: 10450-60-9
• 分子量：: 227.94
• MDL號碼: MFCD00011344
• 分類程式碼代碼: 12352301
• 酶委員會索引編號: 233-937-0
• NACRES: NA.22

屬性

• 品質等級: 200
• 化驗: ≥98% (iodometric)
• 形狀: solid
• 反應適用性: reagent type: oxidant
• pH值: 1.2 (20 °C, 100 g/L in H₂O)
• mp: 122 °C
• 溶解度: ethanol: soluble at 20 °C; water: soluble at 20 °C
• 體積密度: 1400 kg/m³
• 儲存溫度: 15-25°C
• InChI: 1S/H5IO6/c2-1(3,4,5,6)7/h(H5,2,3,4,5,6,7)
• InChI 密鑰: TWLXDPFBEPBAQB-UHFFFAOYSA-N

描述

應用

Periodic acid can be used as a reagent for the oxidative cleavage of 1,2 diols to ketones or aldehydes, and epoxides to aldehydes. It is also used in the oxidative cleavage of various protecting groups such as acetonide, tetrahydropyranyl ether (THP), ethoxyethyl acetals, cyclic acetals, dithioacetals, and oxathioacetals.
It can also be used:

• In the selective N-nitrosation of secondary amines in the presence of sodium nitrite, and wet silica gel.
• As a stoichiometric oxidant with chromium (IV) acetate for the oxidation of tertiary C−H bonds to tertiary alcohols.
• In combination with chromium oxide to oxidize primary alcohols to carboxylic acids; alkylbenzenes to benzoic acids; and cyclic benzyl ethers to the corresponding lactones.
• In the iodination of bulky polyalkyl benzenes in the presence of iodine.
• In the oxidative coupling of polycyclic aromatic hydrocarbons in the presence of aqueous acetic acid.
• In the selective oxidation of sulfides to sulfoxides using FeCl₃ as a catalyst.

分析報告

Assay (iodometric): ≥ 98.0 %
Melting range (lower value): ≥ 124 °C
Melting range (upper value): ≤ 129 °C

安全資訊

• 象形圖: GHS03,GHS05,GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H271 - H314 - H372 - H410
• 防範說明: P210 - P260 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• 危險分類: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Ox. Sol. 1 - Skin Corr. 1B - STOT RE 1 Oral
• 標靶器官: Thyroid
• 儲存類別代碼: 5.1A - Strongly oxidizing hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable