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Key Documents

49797

Supelco

4-Butylresorcinol

analytical standard

同義詞:

4-Butyl-1,3-benzenediol

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About This Item

經驗公式(希爾表示法):
C10H14O2
CAS號碼:
分子量::
166.22
Beilstein:
1942645
MDL號碼:
分類程式碼代碼:
85151701
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

化驗

≥97.0% (GC)

儲存期限

limited shelf life, expiry date on the label

應用

cleaning products
cosmetics
food and beverages
personal care

格式

neat

SMILES 字串

OC1=C(CCCC)C=CC(O)=C1

InChI

1S/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3

InChI 密鑰

CSHZYWUPJWVTMQ-UHFFFAOYSA-N

一般說明

4-n-butylresorcinol is a derivative of resorcinol and a potent human tyrosinase inhibitor. It may be used to decrease skin irritation and is also known to inhibit melanin production.

推薦產品

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象形圖

Exclamation markEnvironment

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

293.0 °F

閃點(°C)

145 °C


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

The efficacy and safety of 4-n-butylresorcinol 0.1% cream for the treatment of melasma: a randomized controlled split-face trial.
Huh SY, et al.
Annals of Dermatology, 22(1), 21-25 (2010)
William Wargniez et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1060, 416-423 (2017-07-05)
In the present study, three laboratories independently compared percutaneous absorption and distribution of 4-n-butylresorcinol, using human skin from five donors. Each laboratory used the same protocol for percutaneous absorption studies but different LC-MS/MS analytical methods to quantify the test compound.
S-J Lee et al.
International journal of cosmetic science, 39(3), 248-255 (2016-10-27)
4-n-butylresorcinol is a competitive inhibitor of tyrosinase and has been used as an antimelanogenic agent. However, its inhibition mechanism in intact cells is not fully understood. To elucidate the cellular mechanism, we compared in vitro and in vivo inhibitory effects

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