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48912-U

Sigma-Aldrich

ProClin 300

pkg of 50 mL, ProClin preservative for use in IVD manufacturing, CMIT/MIT 3 %

同義詞:

3% 5-氯-2-甲基-4-异噻唑啉-3-酮和2-甲基-4-异噻唑啉-3-酮溶液

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About This Item

分類程式碼代碼:
12352201
NACRES:
NA.21

品質等級

形狀

liquid

儲存期限

3 yr

包含

Alkyl Carboxylate

成份

CMIT/MIT, 3%

包裝

pkg of 50 mL

參數

<45 °C operating temperature

顏色

colorless to light yellow

基質

Modified glycol

工作pH值範圍

2.5-8.5

pH值

4.1 (100 g/L)

bp

189 °C

mp

-40 °C

溶解度

water: soluble

密度

1.03 g/cm3

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一般說明

ProClin 防腐剂是一种的水溶性杀菌制剂,通常用于延长试剂的保质期。ProClin 300 由 3% 的 5-氯-2-甲基-4-异噻唑啉-3-酮(CMIT) 和 2-甲基-4-异噻唑啉-3-酮 (MIT) 组成,溶于含有烷基羧酸盐的无盐专有乙二醇稳定剂中。推荐工作 pH 范围为 2.5 - 8.5。

應用

ProClin 300 适用于制备不同的缓冲液,如 ELISA 缓冲液、样品和底物稀释缓冲液,用于单分子阵列(Simoa 分析)和免疫酶分析。此外,ProClin 可用于制备储存缓冲液,以储存与冠状病毒核衣壳蛋白偶联的珠子,并用于血清学多重检测。
ProClin生物灭活剂能够迅速穿透细胞膜,抑制对细胞呼吸至关重要的特定酶,因此一接触微生物有机体就会立即抑制细胞活性。ProClin的多个特定毒性位点可以防止微生物产生高水平的耐药性,使ProClin即使在您的IVD组份的长期存储期间也保持高效。
仅限生物诊断检测和体外诊断检测使用

生化/生理作用

ProClin 产品包含例如 CMIT 和 MIT等活性物质,它们可在四个不同的检查点抑制三羧酸循环,分别为丙酮酸脱氢酶、α-酮戊二酸脱氢酶、琥珀酸脱氢酶和NADH脱氢酶。三羧酸循环的抑制可实现对细菌、真菌和酵母的有效广谱杀灭活性。

法律資訊

ProClin is a trademark of LANXESS Corp.

訊號詞

Danger

危險分類

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

儲存類別代碼

8A - Combustible, corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

244.4 °F - closed cup

閃點(°C)

118 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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