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39405

Sigma-Aldrich

4-(二甲氨基)吡啶

purum, ≥98.0% (NT)

同義詞:

N,N-二甲基-4-吡啶胺, DMAP

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About This Item

經驗公式(希爾表示法):
C7H10N2
CAS號碼:
分子量::
122.17
Beilstein:
110354
EC號碼:
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:
NACRES:
NA.22

等級

purum

品質等級

化驗

≥98.0% (NT)

形狀

crystals
pellets

mp

108-110 °C (lit.)
111-114 °C

溶解度

methanol: 0.1 g/mL, clear, colorless to almost colorless

官能基

amine

SMILES 字串

CN(C)c1ccncc1

InChI

1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3

InChI 密鑰

VHYFNPMBLIVWCW-UHFFFAOYSA-N

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一般說明

4-(二甲基氨基)吡啶通常用作胺、醇、烯醇化物和酚的酰化催化剂。它也可用于羧酸的酯化。众所周知,它在非极性溶剂中有良好的催化活性。

應用

4-(二甲基氨基)吡啶可用于:
  • 作为水溶性金纳米颗粒制备中的封端剂
  • 作为环氧单体聚合的引发剂
  • 作为无电镀制备催化用金纳米颗粒的助剂
  • 通过γ,δ-不饱和羧酸的碘内酯化制备γ-和δ-内酯的催化剂。

酰化反应的高效催化剂

其他說明

超亲核酰化催化剂。综述

訊號詞

Danger

危險分類

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1

標靶器官

Nervous system

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

255.2 °F

閃點(°C)

124 °C

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

A. Hassner
Tetrahedron, 34, 2069-2069 (1978)
E.F. Scriben
Chemical Society Reviews, 13, 129-129 (1983)
Hoefle, G., et al.
Angewandte Chemie (International Edition in English), 90, 602-602 (1978)
Giovanna Cutrone et al.
Carbohydrate polymers, 223, 115085-115085 (2019-08-21)
Nanoparticles made of metal-organic frameworks (nanoMOFs) are becoming of increasing interest as drug carriers. However, engineered coatings such as poly(ethylene glycol) (PEG) based ones are required to prevent nanoMOFs recognition and clearance by the innate immune system, a prerequisite for
Yi Zhang et al.
ACS applied materials & interfaces, 11(50), 46427-46436 (2019-11-26)
A kind of specific cyclodextrin polyrotaxanes (PRs) drug delivery system was developed for an effective drug delivery and enhancing antitumor effect. In this work, we prepared the PR by using α-CD derivatives and dicarboxyl-PEG (Mn = 4200) self-assembling and end-capping

文章

In principle, the seemingly simple formation of a peptide bond can be accomplished using all the procedures available in organic chemistry for the synthesis of carboxylic acid amides. However, due to the presence of various functional groups in natural and unnatural amino acids and particularly the requirement for full retention of chiral integrity, the coupling of amino acids and peptides under mild conditions can be challenging. A plethora of coupling reagents has been developed superseding each other in efficiency and suitability for specific applications (e.g., solid-phase peptide synthesis or fragment condensation).

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