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Key Documents

34012

Supelco

氟西汀 盐酸盐

VETRANAL®, analytical standard

同義詞:

(±)-N-甲基-γ-[4-(三氟甲基)苯氧基]苯丙胺 盐酸盐, LY-110,140 盐酸盐, Prozac®

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About This Item

經驗公式(希爾表示法):
C17H18F3NO · HCl
CAS號碼:
分子量::
345.79
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

產品線

VETRANAL®

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
pharmaceutical (small molecule)

格式

neat

SMILES 字串

CNCCC(C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H

InChI 密鑰

GIYXAJPCNFJEHY-UHFFFAOYSA-N

基因資訊

human ... SLC6A4(6532)

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一般說明

Fluoxetine hydrochloride is an antidepressant drug and a selective serotonin reuptake inhibitor, which is widely used for the treatment of major depressive disorders, obsessive-compulsive disorder and panic fits.

應用

Fluoxetine hydrochloride may be used as an analytical reference standard for the quantification of the analyte in biological fluids using various chromatography techniques.
Fluoxetine hydrochloride may be used as an antidepressant, since it can selectively inhibit the serotonin uptake in the brain. It may also be used in the management of a variety of psychiatric and metabolic derangements.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化/生理作用

选择性羟色胺再摄取抑制剂;抗抑郁剂。

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

法律資訊

经 Eli Lilly and Company 授权销售。
Prozac is a registered trademark of Eli Lilly and Co.
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - STOT RE 2 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

A rapid HPLC-DAD method for the analysis of fluoxetine and norfluoxetine in plasma from overdose patients.
Sabbioni C, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(2), 351-356 (2004)
Molecular Structure of Fluoxetine Hydrochloride, a Highly Selective Serotonin-Uptake Inhibitor
Robertson.WD, et al.
Journal of Medicinal Chemistry, 31, 185-189 (1988)
Study of the interaction between fluoxetine hydrochloride and bovine serum albumin in the imitated physiological conditions by multi-spectroscopic methods
Katrahalli U, et al.
Journal of Luminescence, 130, 211-216 (2010)
LC-MS determination and bioavailability study of loperamide hydrochloride after oral administration of loperamide capsule in human volunteers.
Yu H-J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(2), 421-427 (2004)
Paulina Jedynak et al.
Journal of psychiatric research, 56, 106-111 (2014-06-17)
The neurogenesis hypothesis of major depression has two main facets. One states that the illness results from decreased neurogenesis while the other claims that the very functioning of antidepressants depends on increased neurogenesis. In order to verify the latter, we

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