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Merck
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文件

02000585

水飞蓟宾

mixture of Silybin A and B, primary reference standard

同義詞:

(2R,3R)-3,5,7-三羟基-2-[3-（4-羟基-3-甲氧基苯基）-2-羟甲基-2,3-二氢苯并 [1,4] 二恶英-6-基] 色满-4-酮, 西利马林

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About This Item

經驗公式（希爾表示法）:
C25H22O10
CAS號碼:
802918-57-6
分子量：:
482.44
EC號碼:
245-302-5
分類程式碼代碼:
85151701
NACRES:
NA.24

等級

primary reference standard

品質

mixture of Silybin A and B

儲存期限

limited shelf life, expiry date on the label

製造商／商標名

HWI

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

food and beverages

SMILES 字串

COc1cc(ccc1O)C2Oc3cc(ccc3OC2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O

InChI

1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20?,23-,24?,25+/m0/s1

InChI 密鑰

SEBFKMXJBCUCAI-DBMPWETRSA-N

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相關類別

一般說明

由 HWI pharma services GmbH 生产并鉴定。
通过定量 NMR 测得的准确含量可参见证书。

應用

草药产品分析的标准品。

其他說明

This compound is commonly found in plants of the genus: silybum

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H302

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

Choose from one of the most recent versions:

分析證明 (COA)

Lot/Batch Number
HWI01951-1
HWI01951
HWI01324-2
HWI01324-1
HWI01324

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Yi-Xin Wang et al.
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To investigate the effect of silibinin on proliferation and apoptosis in human gastric cancer cell line MGC803 and its possible mechanisms. Human gastric cancer cell line MGC803 cells were treated with various concentration of silibinin. Cellular viability was assessed by
Suvadra Das et al.
PloS one, 9(7), e101818-e101818 (2014-07-06)
Silybin, is one imminent therapeutic for drug induced hepatotoxicity, human prostate adenocarcinoma and other degenerative organ diseases. Recent evidences suggest that silybin influences gluconeogenesis pathways favorably and is beneficial in the treatment of type 1 and type 2 diabetes. The
Peng Liu et al.
In vitro cellular & developmental biology. Animal, 50(10), 899-908 (2014-08-26)
To investigate the effects of icaritin, an active ingredient extracted from Epimedium Sagittatum (Sieb. et Zucc.), on CCl4-induced liver injury and its possible mechanisms. Hepatocytes isolated from Sprague-Dawley male rats were treated with 3 mmol/L CCl4 for 24 h to
Hong-Li Zhang et al.
Biological & pharmaceutical bulletin, 37(7), 1214-1220 (2014-04-25)
Hepatitis B is the most common serious liver infection in the world. To date, there is still no complete cure for chronic hepatitis B. Natural caffeic acid analogues possess prominent antiviral activity, especially anti-hepatitis B virus (HBV) and anti-human immunodeficiency
Weiquan Zhao et al.
Journal of separation science, 37(17), 2300-2306 (2014-06-14)
Silymarin extracted from Silybum marianum (L.) Gaertn consists of a large number of flavonolignans, of which diastereoisomeric flavonolignans including silybin A and silybin B, and isosilybin A and isosilybin B are the main bioactive components, whose preparation from the crude
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