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一般說明
凝血酶是一种Na+变构丝氨酸蛋白酶。它属于糜蛋白酶家族。凝血酶是由两条多肽链组成,一条含有36个氨基酸残基(A链),另一条有259个残基(B链),两条链通过二硫键共价连接。
凝血酶是凝血因子IIa。它是一种丝氨酸内肽酶,水解肽链和酯键,尤其是在Arg羧基侧的。该酶将纤维蛋白原转化为纤维蛋白。产品含有EDTA和额外的稳定剂。
應用
凝血酶可用于重组RELM(抵抗素样分子家族成员)蛋白的表达和纯化。它被用作血小板在纤维蛋白原 和免疫染色分散。
凝血酶用于凝血研究,医学研究,蛋白质结构分析和生化研究。它被用作血小板刺激物。
生化/生理作用
凝血酶在凝血中有很重要的作用。它作为促凝血因子,能够将纤维蛋白原转化成不能溶解的纤维蛋白结块。通过激活蛋白质C,凝血酶可用作抗凝血剂。
外觀
冻干粉
準備報告
储存条件(工作液):-15至-25℃
抑制剂: DFP, TLCK, PMSF,苯甲脒,α1抗胰蛋白酶α2巨球蛋白,抗凝血酶III,肝素,水蛭素和APMSF
抑制剂: DFP, TLCK, PMSF,苯甲脒,α1抗胰蛋白酶α2巨球蛋白,抗凝血酶III,肝素,水蛭素和APMSF
重構
重组溶液包含20mM EDTA。
注意:
使用塑料管和枪头因为凝血酶会被玻璃表面吸附!
注意:
使用塑料管和枪头因为凝血酶会被玻璃表面吸附!
儲存和穩定性
储存温度2°C至8°C。 (干燥储存!)
其他說明
仅用于生命科学研究。不可用于诊断。
免責聲明
仅供研究使用。在法国,在用于科研目的时(包括进口和出口活动(《公共健康法》第L 1211-1条,第2节))该产品为管制品。购买者(即最终用户)需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Inhalation - STOT RE 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 2
閃點(°F)
does not flash
閃點(°C)
does not flash
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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