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TGFBMAG-64K-01

Millipore

MILLIPLEX® TGFß1磁珠单重检测试剂盒 - 免疫学多重检测

This Immunology Multiplex Assay is used for the simultaneous quantification of the TGF-β1 biomarker in the following species: Mouse/Human/Rat/Pig/Horse/Rabbit/Guinea Pig/Hamster.

同義詞:

Luminex® cytokine immunoassay, Millipore TGF beta kit, transforming growth factor beta 1 kit

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.47

品質等級

200

物種活性

rat, canine, feline, nonhuman primates, mouse, human, pig

製造商／商標名

Milliplex®

assay range

accuracy: 100%
sensitivity: 12 pg/mL
standard curve range: 9.8-2,500 pg/mL

技術

multiplexing: suitable

相容性

configured for Single Plex

檢測方法

fluorometric (Luminex xMAP)

運輸包裝

wet ice

相關類別

一般說明

转化生长因子β(TGFβ)系统属于细胞因子超家族和信号通路成员，在动物界进化上高度保守。TGFβ参与免疫细胞发育、血管生成、伤口愈合、胚胎发育和骨发育过程，在免疫应答、心脏病和肿瘤中起重要作用。正常状态的TGFβ是少数几种能够抑制细胞生长的蛋白，通过使有丝分裂停滞在G1期，促进细胞分化和凋亡。但是，TGFβ信号通路的癌变会使肿瘤细胞能够抵抗TGFβ的正常发挥作用，导致失去调控的增殖发生。初步研究表明，VE-钙粘蛋白可能增强突变的TGFβ信号通路。

MILLIPLEX® TGFβ1单重磁珠检测试剂盒是单因子分析试剂盒，用于定量分析血清、血浆、组织/细胞裂解物和培养上清液中的TGFβ
解决方案。

Luminex® xMAP®平台使用磁珠免疫分析格式，以实现理想的速度和灵敏度，同时定量多种分析物，从而显著提高生产力，同时节省宝贵的样品量。

组套类型：细胞因子/趋化因子

特異性

除了人类TGFβ1，该试剂盒还可以检测下列动物血清中的TGFβ1：马、兔、小鼠、大鼠、小型猪、犬、仓鼠、豚鼠、恒河猴和食蟹猴。但是，准确的交叉反应量并未测定。

應用

  • 分析物：TGFβ1
  • 建议种属：除了人类TGFβ1，该试剂盒还可以检测下列动物血清中的TGFβ1：马、兔、小鼠、大鼠、小型猪、犬、仓鼠、豚鼠、恒河猴和食蟹猴。但是，准确的交叉反应量并未测定。
  • 建议的样本类型：血清、血浆、细胞/组织培养物上清液和裂解物
  • 注：本品需要采用提供的试剂和方法对样品进行酸化处理。
  • 建议的样本稀释方法：血清和血浆样本，在酸化处理后1:30稀释，每孔加样25 μL；细胞/组织培养样本，需要在酸化前稀释（详见说明书）。
  • 检测耗时：在2-8℃下过夜（16-18小时）或在室温（20-25℃）下2小时。
  • 研究类别：炎症&免疫学
  • 研究子类别：心血管病，慢性炎症，免疫病，炎症，类风湿关节炎

包裝

单个试剂盒即可满足您的所有需求。

儲存和穩定性

试剂盒组件的建议储存温度为2 - 8°C。

法律資訊

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Aquatic Chronic 2 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A - Skin Sens. 1

儲存類別代碼

8A - Combustible corrosive hazardous materials

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Jorge Carrascal et al.
European journal of immunology, 46(3), 593-608 (2015-12-08)
Autoreactive B lymphocytes play a key role as APCs in diaebetogenesis. However, it remains unclear whether B-cell tolerance is compromised in NOD mice. Here, we describe a new B lymphocyte transgenic NOD mouse model, the 116C-NOD mouse, where the transgenes
Low-dose gemcitabine depletes regulatory T cells and improves survival in the orthotopic Panc02 model of pancreatic cancer.
Shevchenko, I; Karakhanova, S; Soltek, S; Link, J; Bayry, J; Werner, J; Umansky, V; Bazhin, AV
International Journal of Cancer. Journal International Du Cancer null
Blockade of A2B adenosine receptor reduces left ventricular dysfunction and ventricular arrhythmias 1 week after myocardial infarction in the rat model.
Zhang, H; Zhong, H; Everett, TH; Wilson, E; Chang, R; Zeng, D; Belardinelli, L; Olgin, JE
Heart Rhythm : the Official Journal of the Heart Rhythm Society null
Xiaonan Li et al.
PloS one, 16(5), e0251293-e0251293 (2021-05-14)
Proteins and lipids of milk fat globule membrane (MFGM) and probiotics are immunomodulatory. We hypothesized that Lactobacillus paracasei ssp. paracasei strain F19 (F19) would augment vaccine antibody and T helper 1 type immune responses whereas MFGM would produce an immune
Vera S Donnenberg et al.
Frontiers in immunology, 13, 846235-846235 (2022-03-01)
Metastasis to the pleural and peritoneal cavities is a common terminal pathway for a wide variety of cancers. This article explores how these unique environments both promote aggressive tumor behavior and suppresses anti-tumor immunity, and ways in which local delivery
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