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Merck
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HSCRMAG-32K

Millipore

MILLIPLEX®人可溶性细胞因子受体板-免疫学多重检测试剂盒

Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.

同義詞:

Human Cytokine Receptor Multiplex Kit, Luminex® Human Cytokine Receptor Immunoassay, Millipore Cytokine Receptor Panel

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000

品質等級

200

物種活性

human

製造商／商標名

Milliplex®

assay range

accuracy: 91-104%
sensitivity: 4-208 pg/mL
(Overnight Incubation minDC)
standard curve range: 12.2-50,000 pg/mL
(sIL-4R, sIL-6R, sRAGE, sTNFRI, sTNFRII)
standard curve range: 122.1-500,000 pg/mL
(sEGFR, sIL-1RII, sVEGF-R1, sVEGF-R2, sVEGF-R3)
standard curve range: 24.4-100,000 pg/mL
(sCD30, sgp130, sIL-1RI, sIL-2Rα)
inter-assay cv: <15%
intra-assay cv: <10%

技術

multiplexing: suitable

檢測方法

fluorometric (Luminex xMAP)

運輸包裝

wet ice

相關類別

一般說明

细胞因子受体构成细胞因子生物学的组成部分。与细胞因子一样，细胞因子受体参与了几乎全部疾病状态的正常生理和病理过程。可溶性细胞因子受体天然来自编码膜结合受体的基因，或者是受体本身的直接衍生物。可溶性细胞因子受体参与调节过度的炎症反应和调节免疫事件的发现激发了人们对其作为免疫治疗剂的潜在作用的重大研究兴趣。这些可溶性细胞因子受体中有许多可以抑制其细胞因子配体的结合和生物活性，使其成为非常特异的细胞因子拮抗剂。

MILLIPLEX®人可溶性细胞因子受体检测试剂盒用于同时定量人血清、血浆和细胞/组织培养上清液样品中的14种可溶性细胞因子受体。该试剂盒采用96孔板，包含冻干标准混合物、两个内部检测质控品，可最多可测定38份样品，重复两次。

Luminex® xMAP®平台使用磁珠免疫分析格式，以实现理想的速度和灵敏度，同时定量多种分析物，从而显著提高生产力，同时节省宝贵的样品量。

面板类型：细胞因子/趋化因子

應用

  • 分析物：sCD30，sEGFR，sGP130，sIL-1RI，sIL-1RII，sIL-2Rα，sIL-4R，sIL-6R，sRAGE，sTNFRI，sTNFRII，sVEGFR1，sVEGFR2，sVEGFR3
  • 推荐的样品类型：血清、血浆或组织/细胞裂解物和培养上清液
  • 推荐的样品稀释度：血浆或血清或纯细胞培养上清液的1：5稀释
  • 分析运行时间：过夜
  • 研究类别：炎症 & 免疫学

特點和優勢

通过在此面板中选择可用的分析物来设计多重试剂盒。

其他說明

灵敏度：请参阅试剂盒方案了解单个检测试剂盒的灵敏度。
请联系技术服务部进行稀释度线性研究。

法律資訊

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

標靶器官

Respiratory Tract

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 3

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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存取文件庫

Bryan D Young et al.
International heart journal, 62(5), 1096-1105 (2021-09-22)
While cardiac imaging has improved the diagnosis and risk assessment for cardiac sarcoidosis (CS), treatment regimens have consisted of generalized heart failure therapies and non-specific anti-inflammatory regimens. The overall goal of this study was to perform high-sensitivity plasma profiling of
Sandra Hellberg et al.
Cell reports, 16(11), 2928-2939 (2016-09-15)
Multiple sclerosis (MS) is a chronic inflammatory disease of the CNS and has a varying disease course as well as variable response to treatment. Biomarkers may therefore aid personalized treatment. We tested whether in vitro activation of MS patient-derived CD4+ T cells could
Dai Kimura et al.
Frontiers in pediatrics, 4, 31-31 (2016-04-12)
Lung injury activates multiple pro-inflammatory pathways, including neutrophils, epithelial, and endothelial injury, and coagulation factors leading to acute respiratory distress syndrome (ARDS). Low-dose methylprednisolone therapy (MPT) improved oxygenation and ventilation in early pediatric ARDS without altering duration of mechanical ventilation
Adrián Montes-de-Oca-García et al.
Frontiers in physiology, 13, 885185-885185 (2022-08-09)
This study aimed to analyze the influence of the peroxisome proliferator-activated receptor (PPAR)-gamma coactivator (PGC)-1 alpha (PPARGC1A) gene rs8192678 C>T polymorphism on different health-related parameters in male and female young adults. The PPARGC1A gene rs8192678 polymorphism was ascertained by polymerase

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