HSCRMAG32KPX14

MILLIPLEX^® Human Soluble Cytokine Receptor Panel, HSCRMAG-32K- Immunology Multiplex Assay

Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.

• 同義詞: Human Cytokine Receptor Multiplex Kit, Luminex^® Human Cytokine Receptor Immunoassay, Millipore Cytokine Receptor Panel
• 分類程式碼代碼: 12161503
• eCl@ss: 32161000
• NACRES: NA.47

屬性

• 品質等級: 200
• 物種活性: human
• 製造商／商標名: Milliplex^®
• assay range: accuracy: 91-104%; sensitivity: 4-208 pg/mL; (Overnight Incubation minDC); standard curve range: 12.2-50,000 pg/mL; (sIL-4R, sIL-6R, sRAGE, sTNFRI, sTNFRII); standard curve range: 122.1-500,000 pg/mL; (sEGFR, sIL-1RII, sVEGF-R1, sVEGF-R2, sVEGF-R3); standard curve range: 24.4-100,000 pg/mL; (sCD30, sgp130, sIL-1RI, sIL-2Rα); inter-assay cv: <15%; intra-assay cv: <10%
• 技術: multiplexing: suitable
• 相容性: configured for Premixed
• 檢測方法: fluorometric (Luminex xMAP)
• 運輸包裝: wet ice

描述

一般說明

Cytokine receptors constitute an integral part of cytokine biology. Like cytokines, cytokine receptors are involved in normal physiological and pathological processes of almost all disease states. Soluble cytokine receptors naturally arise from genes encoding membrane- bound receptors or are direct derivatives of the receptors themselves. The discovery that soluble cytokine receptors are involved in regulating excessive inflammatory responses and modulating immune events has stimulated significant research interest in their potential role as immunotherapeutic agents. Many of these soluble cytokine receptors can inhibit the binding and biological activity of their cytokine ligands, making them very specific cytokine antagonists.

MILLIPLEX^® Human Soluble Cytokine Receptor Panel is to be used for the simultaneous quantification of 14 soluble cytokine receptors in human serum, plasma and cell / tissue culture supernatant samples. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Cytokines/Chemokines

特異性

Cross Reactivty
There is no detectable cross-reactivity within the panel.

應用

• Analytes: sCD30, sEGFR, sGP130, sIL-1RI, sIL-1RII, sIL-2Rα, sIL-4R, sIL-6R, sRAGE, sTNFRI, sTNFRII, sVEGFR1, sVEGFR2, sVEGFR3
• Recommended Sample type: Serum, plasma or tissue/cell lysate and culture supernatant
• Recommended Sample dilution: 1:5 dilution for plasma or serum or neat cell culture supernatant
• Assay Run Time: Overnight
• Research Category: Inflammation & Immunology

儲存和穩定性

Recommended storage for kit components is 2 - 8°C.

其他說明

Please contact Technical Service for linearity of dilution.

Sensitivity: Please see kit protocol for individual assay sensitivities.

法律資訊

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 象形圖: GHS08,GHS05,GHS07,GHS09
• 訊號詞: Danger
• 危險聲明: H302 + H312 + H332,H317,H318,H373,H411
• 防範說明: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• 危險分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• 標靶器官: Respiratory Tract
• 儲存類別代碼: 10 - Combustible liquids