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Key Documents

OP66

Sigma-Aldrich

Anti-Rb (Ab-5) Mouse mAb (LM95.1)

liquid, clone LM95.1, Calbiochem®

同義詞:

Anti-Retinoblastoma Associated Protein, Anti-pp105

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About This Item

分類程式碼代碼:
12352203

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

LM95.1, monoclonal

形狀

liquid

包含

≤0.1% sodium azide as preservative

物種活性

human

製造商/商標名

Calbiochem®

儲存條件

do not freeze

同型

IgG1

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

human ... RB1(5925)

一般說明

Purified mouse monoclonal antibody generated by immunizing BALB/c mice with the specified immunogen and fusing splenocytes with NS-1 mouse myeloma cells. Recognizes the ~105 kDa Rb protein.
Recognizes the ~105 kDa Rb protein. Sold under license of U.S. Patent 5,853,988 and corresponding patents.
This Anti-Rb (Ab-5) Mouse mAb (LM95.1) is validated for use in Immunoblotting, Paraffin Sections for the detection of Rb (Ab-5).

免疫原

Epitope: within a 56 kDa C-terminal fragment
Human
recombinant, human Rb

應用

Immunoblotting (1 µg/ml; see application references)

Paraffin Sections (3 µg/ml, see comments and application references)

包裝

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

外觀

In 50 mM sodium phosphate buffer, 0.2% gelatin.

分析報告

Negative Control
Saos cells
Positive Control
ML-1 cells or normal colon tissue

其他說明

Dyson, N., et al. 1992. J. Virol.66, 4606.
Dyson, N., et al. 1990. J. Virol.64, 1353.
Horowitz, J.M., et al. 1989. Science243, 937.
Whyte, P., et al. 1988. Nature334, 124.
Klein, G. 1987. Science238, 1539.
Lee, W.H., et al. 1987. Science235, 1394.
Lee, W.H., et al. 1987. Nature329, 642.
Knudson, A.G. 1971. Proc. Natl. Acad. Sci. USA68, 820.
Pre-treatment with heat or pressure cooker may improve staining of some tissue specimens; this should be determined for each specimen. Antibody should be titrated for optimal results in individual systems.

法律資訊

Sold under license of U.S. Patent 5,853,988 and corresponding patents.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Abstracts from USCAP 2019: Genitourinary Pathology (including renal tumors) (776-992).
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Alessandro Bertolo et al.
Scientific reports, 10(1), 19084-19084 (2020-11-07)
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Tao Wei et al.
mBio, 12(4), e0227721-e0227721 (2021-09-02)
The species specificity of papillomaviruses has been a significant roadblock for performing in vivo pathogenesis studies in common model organisms. The Mus musculus papillomavirus type 1 (MmuPV1) causes cutaneous papillomas that can progress to squamous cell carcinomas in laboratory mice.
Hsi-Hsien Hsieh et al.
Journal of cell science, 130(19), 3272-3281 (2017-08-11)
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