MABS485

Anti-Ido1, clone 8G11 Antibody

clone 8G11, from mouse

• 同義詞: Ido1, Indoleamine 2,3-dioxygenase 1, IDO-1, Indoleamine-pyrrole 2,3-dioxygenase
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 8G11, monoclonal
• 物種活性: mouse
• 技術: flow cytometry: suitable; western blot: suitable
• 同型: IgG2aκ
• NCBI登錄號: NP_002155
• UniProt登錄號: P14902
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... IDO1(3620)

描述

一般說明

Indoleamine 2,3-dioxygenase (IDO) is an enzyme that is responsible for converting tryptophan to kynurenines. IDO is expressed by a wide variety of tissues and can be upregulated by interferon gamma. IDO modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO may be involved in the suppression of the immune response to tumours and blocking the IDO pathway may be a potential target for immunotherapy.

特異性

This antibody does not cross react with Ido2.

免疫原

Recombinant protein corresponding to mouse Ido1.

應用

Anti-Ido1, clone 8G11 Antibody is an antibody against Ido1 for use in Western Blotting, Flow Cytometry.

Western Blotting Analysis: A representative lot detected Ido1 in splenic dendric cells from WT or KO mouse tissue lysate (Oberdan Leo, Universite Libre de Bruxelles).
Flow Cytometry Analysis: A representative lot detected Ido1 in splenic dendric cells from mouse (Oberdan Leo, Universite Libre de Bruxelles).

品質

Evaluated by Western Blotting in Ido1-Flag tag transfected HEK293T cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Ido1 in 10 µg of Ido1-Flag tag transfected HEK293T cell lysate.

標靶描述

~44 kDa observed. Uncharacterized band(s) may appear in some lysates.

外觀

Format: Purified

其他說明

Concentration: Please refer to lot specific datasheet.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable