ABS445

Anti-Caspase-5 Antibody

from rabbit, purified by affinity chromatography

• 同義詞: Caspase-5, CASP-5, ICE(rel)-III, Protease ICH-3, Protease TY, Caspase-5 subunit p202.Caspase-5 subunit p10
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: immunocytochemistry: suitable; immunofluorescence: suitable; western blot: suitable
• UniProt登錄號: P51878
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... CASP5(838)

描述

一般說明

Caspase-5 (CASP5) is a member of the peptidase C14A family that can be divided into the apoptotic and inflammatory caspase subfamilies. Members of this subfamily include caspase-1, -4, -5, and -12. When activated, these caspases result in the cleavage and activation of proinflammatory cytokines such as IL-1beta and IL-18. Caspase-5 is expressed in barely detectable amounts in most tissues except brain, with highest levels being found in lung, liver and skeletal muscle. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts.

特異性

This antibody recognizes the intermediate domain of Caspase-5.

免疫原

Epitope: Intermediate domain

KLH-conjugated linear peptide corresponding to the intermediate domain of human Caspase-5.

應用

Detect Caspase 5 using this rabbit polyclonal antibody, Anti-Caspase-5 Antibody validated for use in western blotting, ICC & Immunofluorescence.

Immunocytochemistry Analysis: 2 µg/mL from a representative lot detected Caspase-5 in P815 cells.

Immunofluorescence Analysis: 2 µg/mL from a representative lot detected Caspase-5 in P815 cells.

Research Category
Signaling

Research Sub Category
Developmental Signaling

品質

Evaluated by Western Blotting in Ramos cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected Caspase-5 in Ramos cell lysate.

標靶描述

~48 kDa observed. Uncharacterized bands may appear in some lysates.

外觀

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Ramos cell lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable