8.20128

Saccharin

for synthesis

• 同義詞: Saccharin
• 經驗公式（希爾表示法）: C₇H₅NO₃S
• CAS號碼: 81-07-2
• 分子量：: 183.18
• MDL號碼: MFCD00005866
• 分類程式碼代碼: 12352115
• 酶委員會索引編號: 201-321-0
• NACRES: NA.22

屬性

• 品質等級: 200
• 化驗: ≥98.0% (acidimetric)
• 形狀: crystals
• mp: 228-230 °C
• 儲存溫度: 2-30°C
• InChI: 1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
• InChI 密鑰: CVHZOJJKTDOEJC-UHFFFAOYSA-N

描述

應用

• Gabapentin-saccharin co-crystals with enhanced physicochemical properties and in vivo absorption formulated as oro-dispersible tablets.: This study presents the formulation of gabapentin-saccharin co-crystals, demonstrating improved solubility and absorption, beneficial for pharmaceutical applications (Soliman et al., 2020, doi: 10.1080/10837450.2019.1687521).


• Improving the solubility, dissolution, and bioavailability of Ibrutinib by preparing it in a coamorphous state with saccharin.: The research focuses on enhancing the bioavailability of Ibrutinib through coamorphous preparation with saccharin, which is significant for cancer treatment (Shi et al., 2019, doi: 10.1016/j.xphs.2019.04.031).

分析報告

Assay (acidimetric): ≥ 98.0 %
Melting range (lower value): ≥ 226 °C
Melting range (upper value): ≤ 230 °C
Identity (IR): passes test

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable