8.05740

2-Mercaptoethanol

for synthesis

• 同義詞: 2-巯基乙醇, β-巯基乙醇, 2-羟乙基硫醇, BME, 硫代二甘醇
• 線性公式: HSCH₂CH₂OH
• CAS號碼: 60-24-2
• 分子量：: 78.13
• Beilstein: 773648
• MDL號碼: MFCD00004890
• 分類程式碼代碼: 12352104
• 酶委員會索引編號: 200-464-6
• NACRES: NA.22

屬性

• 蒸汽密度: 2.69 (vs air)
• 品質等級: 200
• 蒸汽壓力: 1 mmHg ( 20 °C)
• 化驗: ≥99% (GC)
• 形狀: liquid
• 自燃溫度: 295 °C
• 效力: 98-162 mg/kg LD₅₀, oral (Rat); 112-224 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 18 %
• 反應適用性: reagent type: reductant
• 濃度: 14.3 M (pure liquid)
• 折射率: n20/D 1.500 (lit.)
• pH值: 4.5-6 (20 °C, 500 g/L in H₂O)
• bp: 157 °C (lit.)
• mp: <-50 °C
• 轉變溫度: flash point 70.5 °C
• 密度: 1.114 g/mL at 25 °C (lit.)
• 儲存溫度: 2-30°C
• SMILES 字串: OCCS
• InChI: 1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
• InChI 密鑰: DGVVWUTYPXICAM-UHFFFAOYSA-N

描述

應用

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

安全資訊

• 象形圖: GHS05,GHS06,GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H301 + H331 - H310 - H315 - H317 - H318 - H361d - H373 - H410
• 防範說明: P273 - P280 - P301 + P310 - P302 + P352 + P310 - P304 + P340 + P311 - P305 + P351 + P338
• 危險分類: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral
• 儲存類別代碼: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 165.2 °F - closed cup
• 閃點（°C）: 74 °C - closed cup