137151

2-巯基乙醇

EMPROVE^® EVOLVE

• 同義詞: β-巯基乙醇, 2-羟乙基硫醇, BME, 硫代二甘醇
• 線性公式: HSCH₂CH₂OH
• CAS號碼: 60-24-2
• 分子量：: 78.13
• Beilstein: 773648
• MDL號碼: MFCD00004890
• 分類程式碼代碼: 12161504

屬性

• 蒸汽密度: 2.69 (vs air)
• 品質等級: 400
• 蒸汽壓力: 1 mmHg ( 20 °C)
• 形狀: liquid
• expl. lim.: 18 %
• 濃度: 14.3 M (pure liquid); 99.0-101.0 % (w/w)
• 雜質: ≤1.0% related substances (GC) 2,2-Dithiodiethanol
• 折射率: n20/D 1.500 (lit.)
• bp: 157 °C (lit.)
• 密度: 1.114 g/mL at 25 °C (lit.)
• 適合性: corresponds for identity (IR)
• 應用: pharma/biopharma processes
• 儲存溫度: 2-8°C
• SMILES 字串: OCCS
• InChI: 1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
• InChI 密鑰: DGVVWUTYPXICAM-UHFFFAOYSA-N

描述

一般說明

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

As part of our EMPROVE^® Program, our raw materials are offered with EMPROVE^® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

應用

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

分析報告

purity (GC) ≥99.0%

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS05,GHS06,GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H301 + H331 - H310 - H315 - H317 - H318 - H361fd - H373 - H410
• 防範說明: P201 - P260 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P305 + P351 + P338 + P310
• 危險分類: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral
• 儲存類別代碼: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°C）: 74 °C - closed cup