568500

SQ 22536

Cell-permeable adenylate cyclase inhibitor.

• 同義詞: SQ 22536, 9-(Tetrahydro-2ʹ-furyl)adenine
• 經驗公式（希爾表示法）: C₉H₁₁N₅O
• CAS號碼: 17318-31-9
• 分子量：: 205.22
• MDL號碼: MFCD00210216
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: off-white
• 溶解度: DMSO: 25 mg/mL; water: 5 mg/mL
• 運輸包裝: ambient
• 儲存溫度: 2-8°C
• InChI: 1S/C9H11N5O/c10-8-7-9(12-4-11-8)14(5-13-7)6-2-1-3-15-6/h4-6H,1-3H2,(H2,10,11,12)
• InChI 密鑰: UKHMZCMKHPHFOT-UHFFFAOYSA-N

描述

一般說明

Cell-permeable adenylate cyclase inhibitor. Blocks PTH-stimulation of adenylate cyclase (IC₅₀ = 200 µM). Reduces PGE₂-induced inhibition of O₂^·– production.

生化／生理作用

Cell permeable: yes

Primary Target
adenylate cyclase

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 200 µM against adenylate cyclase

警告

Toxicity: Irritant (B)

重構

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 weeks at 4°C.

其他說明

Talpain, E., et al. 1995. Br. J. Pharmacol. 114, 1459.
Tamaoki, J., et al. 1993. Prostaglandins45, 363.
Fabbri, E., et al. 1991. J. Enzyme Inhib.5, 87.
Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable