539149

Proteasome Substrate VI, Fluorogenic

A fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome.

• 同義詞: Proteasome Substrate VI, Fluorogenic, Z-ARR-AMC, 2HCl
• 經驗公式（希爾表示法）: C₃₃H₄₄N₁₀O₇ · 2HCl
• CAS號碼: 90468-18-1
• 分子量：: 765.69
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: white to off-white
• 溶解度: DMSO: 200 mg/mL; 80% acetic acid: 50 mg/mL; methanol: soluble
• 螢光: λ_ex ~380 nm; λ_em ~460 nm
• 運輸包裝: ambient
• 儲存溫度: −20°C

描述

一般說明

A fluorogenic substrate for assaying trypsin-like activity of proteasome. Also serves as a substrate for cathepsin B. Excitation max: 360-380 nm; emission max.: 430-460 nm.

A fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome. Also reported to be a specific substrate for cathepsin B.

生化／生理作用

Cell permeable: no

Primary Target
Proteasome

Product does not compete with ATP.

Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

序列

Z-Ala-Arg-Arg-AMC

外觀

Supplied as hydrochloride salt.

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C

其他說明

Geier, E., et al. 1999. Science283, 978.
Dick, T.P., et al. 1998. J. Biol. Chem. 273, 25637.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable