推薦產品
品質等級
描述
RTECS - XT8040000
化驗
≥99% (GC)
形狀
crystalline solid
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
desiccated
顏色
white to off-white
溶解度
ethanol: soluble
isopropanol: soluble
methanol: soluble
運輸包裝
ambient
儲存溫度
10-30°C
SMILES 字串
F[S](=O)(=O)Cc1ccccc1
InChI
1S/C7H7FO2S/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2
InChI 密鑰
YBYRMVIVWMBXKQ-UHFFFAOYSA-N
一般說明
丝氨酸蛋白酶的不可逆抑制剂。其作用机理类似于氟磷酸二异丙酯。PMSF引起活性位点丝氨酸残基的磺酰化。还报告抑制未成熟胸腺细胞中的核小体间DNA片段化。有关更稳定的相关抑制剂，请参见AEBSF（目录号101500）。
生化／生理作用
主要靶标
丝氨酸蛋白酶
丝氨酸蛋白酶
产物不与ATP竞争。
可逆：否
细胞渗透性：否
警告
毒性：腐蚀性（L）
重構
pH 7.5下t½ = 1小时。有效浓度：50 μM。
在复溶后存放于冰箱（4°C）。储备溶液在4°C下可稳定保存至多9个月。
其他說明
Seitz, R., et al. 1993.Int. J. Cancer53, 514.
Weaver, V.M., et al. 1993.Biochem.Cell.Biol.71, 488.
Bourgain, R.H., et al. 1992.Adv.Exp.Med. Biol.316, 427.
Chang, C.T., et al. 1992.Biochem.Int.28, 707.
Weaver, V.M., et al. 1993.Biochem.Cell.Biol.71, 488.
Bourgain, R.H., et al. 1992.Adv.Exp.Med. Biol.316, 427.
Chang, C.T., et al. 1992.Biochem.Int.28, 707.
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法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral - Skin Corr. 1B
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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