444235-M

MMP-13 Substrate, Fluorogenic

A quenched fluorescence substrate for MMP-13 (collagenase-3; k_cat/Km = 1.09 x 10⁶ M⁻¹s⁻¹).

• 同義詞: MMP-13 Substrate, Fluorogenic, Collagenase-3 Substrate, Fluorogenic
• 經驗公式（希爾表示法）: C₅₁H₆₅N₁₃O₁₅
• 分子量：: 1100.14
• 分類程式碼代碼: 12352200

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: lyophilized solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated; protect from light
• 顏色: yellow
• 溶解度: DMSO: 5 mg/mL
• 螢光: λ_ex ~325 nm; λ_em ~393 nm
• 儲存溫度: −20°C

描述

一般說明

A quenched fluorescence substrate for MMP-13 (collagenase-3; k_cat/K_m = 1.09 x 10⁶ M^-1s^-1). Less efficient as a substrate for MMP-1 (fibroblast collagenase) or MMP-8 (neutrophil collagenase).

A quenched fluorescence substrate for MMP-13 (collagenase-3; k_cat/K_m = 1.09 x 10⁶ M^-1s^-1; excitation maximum: ~325 nm; emission maximum: ~393 nm). Less efficient as a substrate for MMP-1 (fibroblast collagenase) or MMP-8 (neutrophil collagenase).

生化／生理作用

Primary Target
A quenched fluorescence substrate for MMP-13 (collagenase-3)

kcat/Km = 1.09 x 106 M⁻¹ sec⁻¹ for MMP-13 (collagenase-3)

警告

Toxicity: Standard Handling (A)

序列

MCA-Pro-Cha-Gly-Nva-His-Ala-Dpa-NH₂ [Cha = L-cyclohexylalanine; Dpa = 3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl; Nva = L-norvaline]

外觀

Supplied as a trifluoroacetate salt.

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他說明

Knauper, V., et al. 1996. J. Biol. Chem. 271, 1544.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable